Auxiliary partial orthotopic liver transplantation for acute liver failure.
Acute liver failure
Aetiology
Auxiliary partial orthotopic liver transplantation
Outcomes
Journal
Annals of the Royal College of Surgeons of England
ISSN: 1478-7083
Titre abrégé: Ann R Coll Surg Engl
Pays: England
ID NLM: 7506860
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
pubmed:
30
11
2018
medline:
20
3
2019
entrez:
29
11
2018
Statut:
ppublish
Résumé
Auxiliary partial orthotopic liver transplantation (APOLT) in acute liver failure acts as a bridge to native liver regeneration with potential for immunosuppression free survival. While technical concerns limit its universal acceptance, the indications in acute liver failure also need to be examined for this procedure to ultimately succeed. We present the case of an eight-month-old girl with cryptogenic acute liver failure who underwent APOLT. She developed postoperative liver dysfunction, most likely owing to the persistence of the diseased native liver, ultimately leading to an orthotopic retransplantation. She remains well on follow-up review. A tempered approach to selecting patients for APOLT (especially with regard to aetiology of acute liver failure) makes it a safe and effective alternative to orthotopic liver transplantation.
Identifiants
pubmed: 30482030
doi: 10.1308/rcsann.2018.0204
pmc: PMC6400919
doi:
Substances chimiques
Aspartate Aminotransferases
EC 2.6.1.1
Bilirubin
RFM9X3LJ49
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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