Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney.
NCC
SPAK
hypokalemic nephropathy
microtubules
trafficking
Journal
American journal of physiology. Renal physiology
ISSN: 1522-1466
Titre abrégé: Am J Physiol Renal Physiol
Pays: United States
ID NLM: 100901990
Informations de publication
Date de publication:
01 02 2019
01 02 2019
Historique:
pubmed:
30
11
2018
medline:
26
11
2019
entrez:
29
11
2018
Statut:
ppublish
Résumé
Hypokalemia contributes to the progression of chronic kidney disease, although a definitive pathophysiological theory to explain this remains to be established. K
Identifiants
pubmed: 30484345
doi: 10.1152/ajprenal.00464.2018
pmc: PMC6397373
doi:
Substances chimiques
Biomarkers
0
Multienzyme Complexes
0
Protein Serine-Threonine Kinases
EC 2.7.11.1
STK39 protein, human
EC 2.7.11.1
WNK Lysine-Deficient Protein Kinase 1
EC 2.7.11.1
WNK1 protein, human
EC 2.7.11.1
WNK4 protein, human
EC 2.7.11.1
Potassium
RWP5GA015D
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
F292-F300Subventions
Organisme : BLRD VA
ID : I01 BX002228
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK051496
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK054983
Pays : United States
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