Furosemide reduces BK-αβ4-mediated K

Acid-Base Equilibrium Animals Diet Female Furosemide / pharmacology Hydrogen-Ion Concentration Kidney / drug effects Large-Conductance Calcium-Activated Potassium Channel alpha Subunits / metabolism Large-Conductance Calcium-Activated Potassium Channel beta Subunits / deficiency Male Mice, Inbred C57BL Mice, Knockout Potassium / blood Renal Elimination / drug effects Sodium Potassium Chloride Symporter Inhibitors / pharmacology Vacuolar Proton-Translocating ATPases / metabolism
furosemide high-K diet large conductance Ca-activated K urine pH

Journal

American journal of physiology. Renal physiology
ISSN: 1522-1466
Titre abrégé: Am J Physiol Renal Physiol
Pays: United States
ID NLM: 100901990

Informations de publication

Date de publication:
01 02 2019
Historique:
pubmed: 30 11 2018
medline: 26 11 2019
entrez: 29 11 2018
Statut: ppublish

Résumé

Special high-K diets have cardioprotective effects and are often warranted in conjunction with diuretics such as furosemide for treating hypertension. However, it is not understood how a high-K diet (HK) influences the actions of diuretics on renal K

Identifiants

DOI: 10.1152/ajprenal.00223.2018 PMID: 30484346 PMC: PMC6397375
pubmed: 30484346
doi: 10.1152/ajprenal.00223.2018
pmc: PMC6397375
doi:

Substances chimiques

Kcnmb4 protein, mouse 0
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits 0
Large-Conductance Calcium-Activated Potassium Channel beta Subunits 0
Sodium Potassium Chloride Symporter Inhibitors 0
Furosemide 7LXU5N7ZO5
Vacuolar Proton-Translocating ATPases EC 3.6.1.-
Potassium RWP5GA015D

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

F341-F350

Subventions

Organisme : NIDDK NIH HHS
ID : F30 DK108456
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK071014
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK092474
Pays : United States

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Auteurs

Bangchen Wang (B)

Department of Cellular and Integrative Physiology, University of Nebraska Medical Center , Omaha, Nebraska.

Jun Wang-France (J)

Department of Cellular and Integrative Physiology, University of Nebraska Medical Center , Omaha, Nebraska.

Huaqing Li (H)

Department of Cellular and Integrative Physiology, University of Nebraska Medical Center , Omaha, Nebraska.

Steven C Sansom (SC)

Department of Cellular and Integrative Physiology, University of Nebraska Medical Center , Omaha, Nebraska.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Équilibre acido-basique › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Eucaryotes › Animaux › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Sulfones › Sulfonamides › Sulfamides › Furosémide › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques calcium-dépendants › Canaux potassiques calcium-dépendants de grande conductance › Sous-unités alpha des canaux potassiques calcium-dépendants de grande conductance › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques calcium-dépendants › Canaux potassiques calcium-dépendants de grande conductance › Sous-unités bêta des canaux potassiques calcium-dépendants de grande conductance › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux légers › Potassium › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques des voies urinaires › Élimination rénale › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Diurétiques › Inhibiteurs du symport chlorure potassium sodium › Furosemide reduces BK-αβ4-mediated K
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs de cations › Pompes à protons › Proton-Translocating ATPases › Vacuolar Proton-Translocating ATPases › Furosemide reduces BK-αβ4-mediated K