Preparation, Characterization and Biological Activity of Cathelicidin-BF-30-Loaded Poly(LA-co-MA) Microspheres.


Journal

Journal of nanoscience and nanotechnology
ISSN: 1533-4880
Titre abrégé: J Nanosci Nanotechnol
Pays: United States
ID NLM: 101088195

Informations de publication

Date de publication:
01 04 2019
Historique:
entrez: 30 11 2018
pubmed: 30 11 2018
medline: 1 6 2021
Statut: ppublish

Résumé

Antimicrobial peptides have a great potential to replace antibiotics in the treatment of bacterial infections. In order to improve the its stability, the antimicrobial peptides were incorporated in poly(L-lactic acid-co-D,L-mandelic acid) (LA-co-MA) microspheres prepared by a double emulsion solvent evaporation method. In this study, the microspheres obtained had a mean particle size of 2.75±0.2

Identifiants

pubmed: 30487016
doi: 10.1166/jnn.2019.16422
doi:

Substances chimiques

Antimicrobial Cationic Peptides 0
Polylactic Acid-Polyglycolic Acid Copolymer 1SIA8062RS
Polyglycolic Acid 26009-03-0
Lactic Acid 33X04XA5AT
Cathelicidins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2435-2442

Auteurs

Yunjiao Wang (Y)

Department of Engineering Research Center of Biopolymer Functional Materials of Yunnan, Yunnan Minzu University, Kunming 650500, China.

Shanrong Wang (S)

Department of Yunnan Rural Leader College, Yunnan Agricultural University, Heilongtan 650201 Kunming, China.

Hongli Li (H)

Department of Engineering Research Center of Biopolymer Functional Materials of Yunnan, Yunnan Minzu University, Kunming 650500, China.

Yueli Bao (Y)

Department of Engineering Research Center of Biopolymer Functional Materials of Yunnan, Yunnan Minzu University, Kunming 650500, China.

Haiyun Chen (H)

Department of Engineering Research Center of Biopolymer Functional Materials of Yunnan, Yunnan Minzu University, Kunming 650500, China.

Minglong Yuan (M)

Department of Engineering Research Center of Biopolymer Functional Materials of Yunnan, Yunnan Minzu University, Kunming 650500, China.

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Classifications MeSH