Possible artifacts in dynamic CEST MRI due to motion and field alterations.


Journal

Journal of magnetic resonance (San Diego, Calif. : 1997)
ISSN: 1096-0856
Titre abrégé: J Magn Reson
Pays: United States
ID NLM: 9707935

Informations de publication

Date de publication:
01 2019
Historique:
received: 21 08 2018
revised: 09 11 2018
accepted: 12 11 2018
pubmed: 1 12 2018
medline: 17 7 2020
entrez: 1 12 2018
Statut: ppublish

Résumé

Dynamic CEST studies such as dynamic glucose enhanced imaging, have gained a lot of attention recently. The expected CEST effects after injection are rather small in tissue especially at clinical field strengths (0.5-2%). Small movements during the dynamic CEST measurement together with a subtraction-based evaluation can lead to pseudo CEST effects of the same order of magnitude. These artifacts are studied herein. A brain tumor patient 3D-CEST baseline scan without glucose injection performed at 3 T is used to generate a virtual dynamic measurement introducing different kinds of simulated motion and B Minor motion (0.6 mm translations) and B Correction or mitigation for small motions is crucial for dynamic CEST imaging, especially in subjects with lesions. Concomitant B

Identifiants

pubmed: 30500568
pii: S1090-7807(18)30303-3
doi: 10.1016/j.jmr.2018.11.002
pii:
doi:

Substances chimiques

Contrast Media 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

16-22

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Moritz Zaiss (M)

High-field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany. Electronic address: moritz.zaiss@tuebingen.mpg.de.

Kai Herz (K)

High-field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.

Anagha Deshmane (A)

High-field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.

Mina Kim (M)

Brain Repair & Rehabilitation, Institute of Neurology, University College London, United Kingdom.

Xavier Golay (X)

Brain Repair & Rehabilitation, Institute of Neurology, University College London, United Kingdom.

Tobias Lindig (T)

Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University Tübingen, Tübingen, Germany.

Benjamin Bender (B)

Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University Tübingen, Tübingen, Germany.

Ulrike Ernemann (U)

Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University Tübingen, Tübingen, Germany.

Klaus Scheffler (K)

High-field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany; Department of Biomedical Magnetic Resonance, Eberhard-Karls University Tübingen, Tübingen, Germany.

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Classifications MeSH