Lecithin soybean phospholipid nano-transfersomes as potential carriers for transdermal delivery of the human growth hormone.


Journal

Journal of cellular biochemistry
ISSN: 1097-4644
Titre abrégé: J Cell Biochem
Pays: United States
ID NLM: 8205768

Informations de publication

Date de publication:
06 2019
Historique:
received: 13 10 2018
accepted: 12 11 2018
pubmed: 7 12 2018
medline: 21 7 2020
entrez: 4 12 2018
Statut: ppublish

Résumé

Pharmaceutical molecules such as peptides and proteins are usually injected into the body. Numerous efforts have been made to find new noninvasive ways to administer these peptides. In this study, highly flexible vesicles (transfersomes [TFs]) were designed as a new modern transdermal drug delivery system for systemic drug administration through the skin, which had also been evaluated in vitro. In this study, two growth hormone-loaded TF formulations were prepared, using soybean lecithin and two different surfactants; F

Identifiants

pubmed: 30506803
doi: 10.1002/jcb.28176
doi:

Substances chimiques

Lecithins 0
Phospholipids 0
Deoxycholic Acid 005990WHZZ
Human Growth Hormone 12629-01-5
Sodium Dodecyl Sulfate 368GB5141J

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9023-9033

Informations de copyright

© 2018 Wiley Periodicals, Inc.

Auteurs

Maryam Kateh Shamshiri (M)

Department of Biology, Faculty of Science, Islamic Azad University, Science and Research Branch, Tehran, Iran.

Amir Abbas Momtazi-Borojeni (AA)

Division of Nanotechnology Research Center, Bu-Ali Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Medical Biotechnology, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Mahvash Khodabandeh Shahraky (M)

Division of Industrial and Environmental Biotechnology (IIEB), National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.

Fatemeh Rahimi (F)

Division of Industrial and Environmental Biotechnology (IIEB), National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.

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Classifications MeSH