How copper ions and membrane environment influence the structure of the human and chicken tandem repeats domain?
Copper ions
Histidine residues
Membrane mimicking environment
Micelles
Prion proteins
Journal
Journal of inorganic biochemistry
ISSN: 1873-3344
Titre abrégé: J Inorg Biochem
Pays: United States
ID NLM: 7905788
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
18
08
2018
revised:
19
11
2018
accepted:
21
11
2018
pubmed:
12
12
2018
medline:
18
12
2019
entrez:
12
12
2018
Statut:
ppublish
Résumé
Prion proteins (PrPs) from different species have the enormous ability to anchor copper ions. The N-terminal domain of human prion protein (hPrP) contains four tandem repeats of the -PHGGGWGQ- octapeptide sequence. This octarepeat domain can bind up to four Cu
Identifiants
pubmed: 30529722
pii: S0162-0134(18)30493-8
doi: 10.1016/j.jinorgbio.2018.11.012
pii:
doi:
Substances chimiques
Membrane Lipids
0
Micelles
0
Sodium Dodecyl Sulfate
368GB5141J
Copper
789U1901C5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
143-153Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.