Biofilms in hospital effluents as a potential crossroads for carbapenemase-encoding strains.

Anti-Bacterial Agents / pharmacology Bacterial Physiological Phenomena Biofilms Drug Resistance, Bacterial France Hospitals Imipenem / pharmacology Medical Waste / analysis Microbial Sensitivity Tests
Biofilm Carbapenem Carbapenemase Hospital effluent Plasmids

Journal

The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500

Informations de publication

Date de publication:
20 Mar 2019
Historique:
received: 06 09 2018
revised: 09 11 2018
accepted: 28 11 2018
pubmed: 12 12 2018
medline: 27 2 2019
entrez: 12 12 2018
Statut: ppublish

Résumé

Bacterial resistance to carbapenem, which is mainly due to the successful dissemination of carbapenemase-encoding genes, has become a major health problem. Few studies have aimed to characterize the level of resistance in the environment, notably in hospital wastewater, which is a likely hotspot for exchange of antibiotic resistance genes. In this work, we looked for the presence of imipenem-resistant bacteria and imipenem in the effluent of the teaching hospital of Clermont-Ferrand, France. Selective growth of bacteria from 14-day old biofilms formed in the pipe sewer showed that 22.1% of the isolates were imipenem-resistant and identified as Aeromonas (n = 23), Pseudomonas (n = 10), Stenotrophomonas (n = 4) and Acinetobacter (n = 1). Fifteen of these strains harbored acquired carbapenemase-encoding genes bla

Identifiants

DOI: 10.1016/j.scitotenv.2018.11.427 PMID: 30530220
pubmed: 30530220
pii: S0048-9697(18)34782-X
doi: 10.1016/j.scitotenv.2018.11.427
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Medical Waste 0
Imipenem 71OTZ9ZE0A

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7-15

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

J Ory (J)

Université Clermont Auvergne, CNRS, Laboratoire "Microorganismes: Génome et Environnement", F-63000 Clermont-Ferrand, France; Service d'hygiène hospitalière, CHU de Clermont-Ferrand, Clermont-Ferrand, France.

G Bricheux (G)

Université Clermont Auvergne, CNRS, Laboratoire "Microorganismes: Génome et Environnement", F-63000 Clermont-Ferrand, France.

F Robin (F)

Laboratoire de Bactériologie & CNR de la Résistance aux Antibiotiques, CHU de Clermont-Ferrand, Clermont-Ferrand, France; Université Clermont Auvergne, Inserm, M2ISH, F-63000 Clermont-Ferrand, France.

A Togola (A)

Bureau de recherches géologiques et minières (BRGM), 3 avenue Claude Guillemin, F-45100 Orléans, France.

C Forestier (C)

Université Clermont Auvergne, CNRS, Laboratoire "Microorganismes: Génome et Environnement", F-63000 Clermont-Ferrand, France.

O Traore (O)

Université Clermont Auvergne, CNRS, Laboratoire "Microorganismes: Génome et Environnement", F-63000 Clermont-Ferrand, France; Service d'hygiène hospitalière, CHU de Clermont-Ferrand, Clermont-Ferrand, France. Electronic address: otraore@chu-clermontferrand.fr.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques bactériens › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Phénomènes microbiologiques › Biofilms › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance microbienne aux médicaments › Résistance bactérienne aux médicaments › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Régions géographiques › Europe › France › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Établissements de santé › Hôpitaux › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Carbapénèmes › Thiénamycine › Imipénem › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Déchets › Déchets médicaux › Biofilms in hospital effluents as a potential...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Biofilms in hospital effluents as a potential...