Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
centrosome
genome stability
intron retention
mitosis
nuclear RNAi
splicing
Journal
RNA (New York, N.Y.)
ISSN: 1469-9001
Titre abrégé: RNA
Pays: United States
ID NLM: 9509184
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
06
12
2018
accepted:
20
12
2018
pubmed:
13
12
2018
medline:
26
3
2019
entrez:
13
12
2018
Statut:
ppublish
Résumé
The accurate inheritance of genetic material is a basic necessity in all domains of life and an unexpectedly large number of RNA processing factors are required for mitotic progression and genome stability. NRDE2 (nuclear RNAi defective-2) is an evolutionarily conserved protein originally discovered for its role in nuclear RNA interference (RNAi) and heritable gene silencing in
Identifiants
pubmed: 30538148
pii: rna.069773.118
doi: 10.1261/rna.069773.118
pmc: PMC6380277
doi:
Substances chimiques
RNA Precursors
0
RNA Splicing Factors
0
RNA, Small Interfering
0
RNA-Binding Proteins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
352-363Subventions
Organisme : NIA NIH HHS
ID : R01 AG033921
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM088289
Pays : United States
Organisme : NIH HHS
ID : R01AG033921
Pays : United States
Informations de copyright
© 2019 Jiao et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.
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