Antidiarrheal activity of α-terpineol in mice.

Animals Antidiarrheals / pharmacology Castor Oil / toxicity Cyclohexane Monoterpenes Cyclohexenes / pharmacology Diarrhea / chemically induced Dose-Response Relationship, Drug Female Gastrointestinal Motility / drug effects Male Mice Monoterpenes / pharmacology
Castor oil Cholera Diarrhea GM1 receptor Monoterpenes Prostaglandin E(2)

Journal

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
ISSN: 1950-6007
Titre abrégé: Biomed Pharmacother
Pays: France
ID NLM: 8213295

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 16 07 2018
revised: 22 11 2018
accepted: 27 11 2018
pubmed: 13 12 2018
medline: 23 4 2019
entrez: 13 12 2018
Statut: ppublish

Résumé

Diarrhea is one of the leading causes of infant death in the world accounting for high child mortality rate. It is also present in different pathophysiologies related to several etiological agents. The aim of this study is to investigate the antidiarrheal effect of α -Terpineol (α-TPN) in different diarrhea models in rodents. The antidiarrheal effect of α-TPN in the treatment of acute diarrhea and enteropooling induced by castor oil or PGE

Identifiants

DOI: 10.1016/j.biopha.2018.11.131 PMID: 30540974
pubmed: 30540974
pii: S0753-3322(18)34643-2
doi: 10.1016/j.biopha.2018.11.131
pii:
doi:

Substances chimiques

Antidiarrheals 0
Cyclohexane Monoterpenes 0
Cyclohexenes 0
Monoterpenes 0
alpha-terpineol 21334LVV8W
Castor Oil 8001-79-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

631-640

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

Auteurs

Polyanna Dos Santos Negreiros (P)

Medicinal Plants Research Center (NPPM), Federal University of Piauí, 64.049-550, Teresina, PI, Brazil.

Douglas Soares da Costa (DS)

Medicinal Plants Research Center (NPPM), Federal University of Piauí, 64.049-550, Teresina, PI, Brazil.

Valdelânia Gomes da Silva (VG)

Medicinal Plants Research Center (NPPM), Federal University of Piauí, 64.049-550, Teresina, PI, Brazil.

Izabela Borges de Carvalho Lima (IB)

Medicinal Plants Research Center (NPPM), Federal University of Piauí, 64.049-550, Teresina, PI, Brazil.

Daniel Barbosa Nunes (DB)

Medicinal Plants Research Center (NPPM), Federal University of Piauí, 64.049-550, Teresina, PI, Brazil.

Francisca Beatriz de Melo Sousa (FB)

Laboratory of Experimental Physiopharmacology (LAFFEX), Federal University of Piauí, 64.202-020, Parnaíba, PI, Brazil.

Thiago de Souza Lopes Araújo (T)

Laboratory of Experimental Physiopharmacology (LAFFEX), Federal University of Piauí, 64.202-020, Parnaíba, PI, Brazil.

Jand Venes Rolim Medeiros (JVR)

Laboratory of Experimental Physiopharmacology (LAFFEX), Federal University of Piauí, 64.202-020, Parnaíba, PI, Brazil.

Rosimeire Ferreira Dos Santos (RF)

Medicinal Plants Research Center (NPPM), Federal University of Piauí, 64.049-550, Teresina, PI, Brazil.

Rita de Cássia Meneses Oliveira (R)

Medicinal Plants Research Center (NPPM), Federal University of Piauí, 64.049-550, Teresina, PI, Brazil. Electronic address: menesesoliveira@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents gastro-intestinaux › Antidiarrhéiques › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Préparations à base de plantes › Huiles végétales › Huile de ricin › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Monoterpènes › Cyclohexane monoterpenes › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures alicycliques › Cyclohexanes › Cyclohexènes › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes digestifs › Diarrhée › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Motilité gastrointestinale › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Antidiarrheal activity of α-terpineol in mice.
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Monoterpènes › Antidiarrheal activity of α-terpineol in mice.