Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae.
Peribunyaviridae
Triniti virus
arbovirus
phylogenetic analysis
serologic tests
ultrastructure
Journal
The Journal of general virology
ISSN: 1465-2099
Titre abrégé: J Gen Virol
Pays: England
ID NLM: 0077340
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
pubmed:
15
12
2018
medline:
24
10
2019
entrez:
15
12
2018
Statut:
ppublish
Résumé
Triniti virus (TNTV) has been isolated in Trinidad and Tobago and in Brazil. To date little is known about this virus, which is classified as an ungrouped virus within the family Togaviridae. Here, three isolates of TNTV were characterized both genetically and antigenically. The genome was shown to contain three RNA segments: small (S), medium (M) and large (L). Genome organization, protein sizes and protein motifs were similar to those of viruses in the genus Orthobunyavirus, family Peribunyaviridae. Antigenic reactivity revealed the three TNTV isolates to be closely related, but no serologic cross-reaction with other orthobunyaviruses. Morphological observation by transmission electron microscopy indicated that virus size and symmetry were compatible with those of viruses in the family Peribunyaviridae. Our serological, morphological and molecular results support the taxonomic reclassification of TNTV as a member of the genus Orthobunyavirus, family Peribunyaviridae.
Identifiants
pubmed: 30547856
doi: 10.1099/jgv.0.001196
pmc: PMC7011695
doi:
Substances chimiques
Antigens, Viral
0
RNA, Viral
0
Viral Proteins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
137-144Subventions
Organisme : NIAID NIH HHS
ID : R24 AI120942
Pays : United States
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