A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics.
ChIP-sequencing (ChIP-seq)
H3.3
Histone variant
chromatin
epigenetics
interferon
transcription
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
08 02 2019
08 02 2019
Historique:
received:
27
08
2018
revised:
09
11
2018
pubmed:
16
12
2018
medline:
27
6
2019
entrez:
16
12
2018
Statut:
ppublish
Résumé
The variant histone H3.3 is incorporated into the genome in a transcription-dependent manner. This histone is thus thought to play a role in epigenetic regulation. However, our understanding of how H3.3 controls gene expression and epigenome landscape has remained incomplete. This is partly because precise localization of H3.3 in the genome has been difficult to decipher particularly for cells
Identifiants
pubmed: 30552116
pii: S0021-9258(20)36837-X
doi: 10.1074/jbc.RA118.005550
pmc: PMC6369307
doi:
Substances chimiques
Histones
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1904-1914Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest with the contents of this article.
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