Mahesh Bachu

Affiliations

Molecular Genetics of Immunity Section, Division of Developmental Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Publications (10)

HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis.

Cell reports

Avec: Chao Chen , Ming-An Sun , Claude Warzecha , Mahesh Bachu , Anup Dey , Tiyun Wu , Peter D Adams , Todd Macfarlan , Paul Love , Keiko Ozato

IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral Response.

Frontiers in immunology

Avec: Debasis Panda , Erisa Gjinaj , Mahesh Bachu , Erica Squire , Hilary Novatt , Keiko Ozato , Ronald L Rabin

BRD4 directs mitotic cell division by inhibiting DNA damage.

bioRxiv : the preprint server for biology

Avec: Tiyun Wu , Haitong Hou , Anup Dey , Mahesh Bachu , Xiongfong Chen , Jan Wisniewski , Fuki Kudoh , Chao Chen , Sakshi Chauhan , Hua Xiao , Richard Pan , Keiko Ozato

Bromodomain protein BRD4 directs mitotic cell division of mouse fibroblasts by inhibiting DNA damage.

iScience

Avec: Tiyun Wu , Haitong Hou , Anup Dey , Mahesh Bachu , Xiongfong Chen , Jan Wisniewski , Fuki Kudoh , Chao Chen , Sakshi Chauhan , Hua Xiao , Richard Pan , Keiko Ozato

Monocyte Subsets With High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Amitabh Das , Xiaobei Wang , Jessica Kang , Alyssa Coulter , Amol C Shetty , Mahesh Bachu , Stephen R Brooks , Stefania Dell'Orso , Brian L Foster , Xiaoxuan Fan , Keiko Ozato , Martha J Somerman , Vivek Thumbigere-Math

Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice.

Nature communications

Avec: Edd Ricker , Michela Manni , Danny Flores-Castro , Daniel Jenkins , Sanjay Gupta , Juan Rivera-Correa , Wenzhao Meng , Aaron M Rosenfeld , Tania Pannellini , Mahesh Bachu , Yurii Chinenov , Peter K Sculco , Rolf Jessberger , Eline T Luning Prak , Alessandra B Pernis

Inactivating Mutation in IRF8 Promotes Osteoclast Transcriptional Programs and Increases Susceptibility to Tooth Root Resorption.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Vivek Thumbigere-Math , Brian L Foster , Mahesh Bachu , Hiroaki Yoshii , Stephen R Brooks , Alyssa Coulter , Michael B Chavez , Sumihito Togi , Anthony L Neely , Zuoming Deng , Kim C Mansky , Keiko Ozato , Martha J Somerman

IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation.

Nature communications

Avec: Kyuho Kang , Mahesh Bachu , Sung Ho Park , Keunsoo Kang , Seyeon Bae , Kyung-Hyun Park-Min , Lionel B Ivashkiv

A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics.

The Journal of biological chemistry

Avec: Mahesh Bachu , Tomohiko Tamura , Chao Chen , Ankur Narain , Vishal Nehru , Naoyuki Sarai , Sukhendu B Ghosh , Anu Ghosh , Raghuveer Kavarthapu , Maria L Dufau , Keiko Ozato

CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes.

Nature communications

Avec: Chao Yang , Mahesh Bachu , Yong Du , Caroline Brauner , Ruoxi Yuan , Marie Dominique Ah Kioon , Giancarlo Chesi , Franck J Barrat , Lionel B Ivashkiv

Réseau de co-auteurs

Keiko Ozato 7 collaborations

Chao Chen 4 collaborations

Anup Dey 3 collaborations

Tiyun Wu 3 collaborations

Haitong Hou 2 collaborations

Xiongfong Chen 2 collaborations

Jan Wisniewski 2 collaborations

Fuki Kudoh 2 collaborations

Sakshi Chauhan 2 collaborations

Hua Xiao 2 collaborations

Richard Pan 2 collaborations

Alyssa Coulter 2 collaborations

Stephen R Brooks 2 collaborations

Brian L Foster 2 collaborations

Martha J Somerman 2 collaborations

Vivek Thumbigere-Math 2 collaborations

Lionel B Ivashkiv 2 collaborations

Ming-An Sun 1 collaboration

Claude Warzecha 1 collaboration

Peter D Adams 1 collaboration

Todd Macfarlan 1 collaboration

Paul Love 1 collaboration

Debasis Panda 1 collaboration

Erisa Gjinaj 1 collaboration

Erica Squire 1 collaboration

Hilary Novatt 1 collaboration

Ronald L Rabin 1 collaboration

Amitabh Das 1 collaboration

Xiaobei Wang 1 collaboration

Jessica Kang 1 collaboration

Amol C Shetty 1 collaboration

Stefania Dell'Orso 1 collaboration

Xiaoxuan Fan 1 collaboration

Edd Ricker 1 collaboration

Michela Manni 1 collaboration

Danny Flores-Castro 1 collaboration

Daniel Jenkins 1 collaboration

Sanjay Gupta 1 collaboration

Juan Rivera-Correa 1 collaboration

Wenzhao Meng 1 collaboration

Aaron M Rosenfeld 1 collaboration

Tania Pannellini 1 collaboration

Yurii Chinenov 1 collaboration

Peter K Sculco 1 collaboration

Rolf Jessberger 1 collaboration

Eline T Luning Prak 1 collaboration

Alessandra B Pernis 1 collaboration

Hiroaki Yoshii 1 collaboration

Michael B Chavez 1 collaboration

Sumihito Togi 1 collaboration

Anthony L Neely 1 collaboration

Zuoming Deng 1 collaboration

Kim C Mansky 1 collaboration

Kyuho Kang 1 collaboration

Sung Ho Park 1 collaboration

Keunsoo Kang 1 collaboration

Seyeon Bae 1 collaboration

Kyung-Hyun Park-Min 1 collaboration

Tomohiko Tamura 1 collaboration

Ankur Narain 1 collaboration

Vishal Nehru 1 collaboration

Naoyuki Sarai 1 collaboration

Sukhendu B Ghosh 1 collaboration

Anu Ghosh 1 collaboration

Raghuveer Kavarthapu 1 collaboration

Maria L Dufau 1 collaboration

Chao Yang 1 collaboration

Yong Du 1 collaboration

Caroline Brauner 1 collaboration

Ruoxi Yuan 1 collaboration

Marie Dominique Ah Kioon 1 collaboration

Giancarlo Chesi 1 collaboration

Franck J Barrat 1 collaboration