U-Net: deep learning for cell counting, detection, and morphometry.


Journal

Nature methods
ISSN: 1548-7105
Titre abrégé: Nat Methods
Pays: United States
ID NLM: 101215604

Informations de publication

Date de publication:
01 2019
Historique:
received: 26 07 2018
accepted: 19 11 2018
pubmed: 19 12 2018
medline: 25 6 2019
entrez: 19 12 2018
Statut: ppublish

Résumé

U-Net is a generic deep-learning solution for frequently occurring quantification tasks such as cell detection and shape measurements in biomedical image data. We present an ImageJ plugin that enables non-machine-learning experts to analyze their data with U-Net on either a local computer or a remote server/cloud service. The plugin comes with pretrained models for single-cell segmentation and allows for U-Net to be adapted to new tasks on the basis of a few annotated samples.

Identifiants

pubmed: 30559429
doi: 10.1038/s41592-018-0261-2
pii: 10.1038/s41592-018-0261-2
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

67-70

Commentaires et corrections

Type : ErratumIn

Références

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Auteurs

Thorsten Falk (T)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.
BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
CIBSS Centre for Integrative Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany.

Dominic Mai (D)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.
BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
Life Imaging Center, Center for Biological Systems Analysis, Albert-Ludwigs-University, Freiburg, Germany.
SICK AG, Waldkirch, Germany.

Robert Bensch (R)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.
BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
ANavS GmbH, München, Germany.

Özgün Çiçek (Ö)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.

Ahmed Abdulkadir (A)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.
University Hospital of Old Age Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

Yassine Marrakchi (Y)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.
BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
CIBSS Centre for Integrative Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany.

Anton Böhm (A)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.

Jan Deubner (J)

Optophysiology Lab, Institute of Biology III, Albert-Ludwigs-University, Freiburg, Germany.
BrainLinks-BrainTools, Albert-Ludwigs-University, Freiburg, Germany.

Zoe Jäckel (Z)

Optophysiology Lab, Institute of Biology III, Albert-Ludwigs-University, Freiburg, Germany.
BrainLinks-BrainTools, Albert-Ludwigs-University, Freiburg, Germany.

Katharina Seiwald (K)

Optophysiology Lab, Institute of Biology III, Albert-Ludwigs-University, Freiburg, Germany.

Alexander Dovzhenko (A)

Institute of Biology II, Albert-Ludwigs-University, Freiburg, Germany.
ScreenSYS GmbH, Freiburg, Germany.

Olaf Tietz (O)

Institute of Biology II, Albert-Ludwigs-University, Freiburg, Germany.
ScreenSYS GmbH, Freiburg, Germany.

Cristina Dal Bosco (C)

Institute of Biology II, Albert-Ludwigs-University, Freiburg, Germany.

Sean Walsh (S)

Institute of Biology II, Albert-Ludwigs-University, Freiburg, Germany.
ScreenSYS GmbH, Freiburg, Germany.

Deniz Saltukoglu (D)

BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
Center for Biological Systems Analysis (ZBSA), Albert-Ludwigs-University, Freiburg, Germany.
Renal Division, University Medical Centre, Freiburg, Germany.
Spemann Graduate School of Biology and Medicine (SGBM), Albert-Ludwigs-University, Freiburg, Germany.

Tuan Leng Tay (TL)

BrainLinks-BrainTools, Albert-Ludwigs-University, Freiburg, Germany.
Institute of Neuropathology, University Medical Centre, Freiburg, Germany.
Institute of Biology I, Albert-Ludwigs-University, Freiburg, Germany.

Marco Prinz (M)

BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
CIBSS Centre for Integrative Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany.
Institute of Neuropathology, University Medical Centre, Freiburg, Germany.

Klaus Palme (K)

BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
Institute of Biology II, Albert-Ludwigs-University, Freiburg, Germany.

Matias Simons (M)

BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
Center for Biological Systems Analysis (ZBSA), Albert-Ludwigs-University, Freiburg, Germany.
Renal Division, University Medical Centre, Freiburg, Germany.
Paris Descartes University-Sorbonne Paris Cité, Imagine Institute, Paris, France.

Ilka Diester (I)

Optophysiology Lab, Institute of Biology III, Albert-Ludwigs-University, Freiburg, Germany.
BrainLinks-BrainTools, Albert-Ludwigs-University, Freiburg, Germany.
Bernstein Center Freiburg, Albert-Ludwigs-University, Freiburg, Germany.

Thomas Brox (T)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany.
BIOSS Centre for Biological Signalling Studies, Freiburg, Germany.
CIBSS Centre for Integrative Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany.
BrainLinks-BrainTools, Albert-Ludwigs-University, Freiburg, Germany.

Olaf Ronneberger (O)

Department of Computer Science, Albert-Ludwigs-University, Freiburg, Germany. ronneber@informatik.uni-freiburg.de.
BIOSS Centre for Biological Signalling Studies, Freiburg, Germany. ronneber@informatik.uni-freiburg.de.
DeepMind, London, UK. ronneber@informatik.uni-freiburg.de.

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