Concentration dependence of in vitro biotransformation rates of hydrophobic organic sunscreen agents in rainbow trout S9 fractions: Implications for bioaccumulation assessment.

Acrylates / chemistry Animals Biotransformation Camphor / analogs & derivatives Cinnamates / chemistry Hydrophobic and Hydrophilic Interactions Liver / metabolism Oncorhynchus mykiss / metabolism Sunscreening Agents / chemistry
Bioaccumulation Biotransformation In vitro-in vivo extrapolation Rainbow trout Sunscreens Ultraviolet filters

Journal

Environmental toxicology and chemistry
ISSN: 1552-8618
Titre abrégé: Environ Toxicol Chem
Pays: United States
ID NLM: 8308958

Informations de publication

Date de publication:
03 2019
Historique:
received: 09 08 2018
revised: 03 10 2018
accepted: 16 12 2018
pubmed: 21 12 2018
medline: 14 6 2019
entrez: 21 12 2018
Statut: ppublish

Résumé

In vitro biotransformation studies were performed to support the bioaccumulation assessment of 3 hydrophobic organic ultraviolet filters (UVFs), 4-methylbenzylidene camphor (4-MBC), 2-ethylhexyl-4-methoxycinnamate (EHMC), and octocrylene. In vitro depletion rate constants (k

Identifiants

DOI: 10.1002/etc.4342 PMID: 30569498 PMC: PMC6477924
pubmed: 30569498
doi: 10.1002/etc.4342
pmc: PMC6477924
mid: NIHMS1525152
doi:

Substances chimiques

Acrylates 0
Cinnamates 0
Sunscreening Agents 0
octylmethoxycinnamate 4Y5P7MUD51
octocrylene 5A68WGF6WM
Camphor 76-22-2
enzacamene 8I3XWY40L9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

548-560

Subventions

Organisme : Intramural EPA
ID : EPA999999
Pays : United States

Informations de copyright

© 2018 SETAC.

Références

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Auteurs

Leslie J Saunders (LJ)

Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.

Simon Fontanay (S)

Department of Biological Engineering, Polytech Clermont-Ferrand, Clermont-Ferrand, France.

John W Nichols (JW)

US Environmental Protection Agency, Duluth, Minnesota.

Frank A P C Gobas (FAPC)

Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
School of Resource and Environmental Management, Simon Fraser University, Burnaby, British Columbia, Canada.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Acrylates › Concentration dependence of in vitro...
questionsmedicales.fr › Eucaryotes › Animaux › Concentration dependence of in vitro...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Biotransformation › Concentration dependence of in vitro...
questionsmedicales.fr › Composés polycycliques › Composés pontés › Composés bicycliques pontés › Monoterpènes de type norbornane › Monoterpènes de type bornane › Camphre › Concentration dependence of in vitro...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides carbocycliques › Cinnamates › Concentration dependence of in vitro...
questionsmedicales.fr › Phénomènes chimiques › Interactions hydrophobes et hydrophiles › Concentration dependence of in vitro...
questionsmedicales.fr › Système digestif › Foie › Concentration dependence of in vitro...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Salmoniformes › Salmonidae › Truite › Oncorhynchus › Oncorhynchus mykiss › Concentration dependence of in vitro...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Radioprotecteurs › Produits antisolaires › Concentration dependence of in vitro...