Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy.

Animals Cyclic N-Oxides Dose-Response Relationship, Radiation Electron Spin Resonance Spectroscopy / methods Free Radicals / analysis Humans Imaging, Three-Dimensional / statistics & numerical data Mice Models, Biological Oxidative Stress Oxygen / chemistry Radiometry Skin / radiation effects Spin Labels Sunlight / adverse effects Swine Tissue Culture Techniques Ultraviolet Rays / adverse effects
Characterization of radical production Human skin Murine skin Paramagnetic resonance spectroscopy Porcine skin Quantitative free radical measurement Skin models Sun irradiation

Journal

Free radical biology & medicine
ISSN: 1873-4596
Titre abrégé: Free Radic Biol Med
Pays: United States
ID NLM: 8709159

Informations de publication

Date de publication:
01 02 2019
Historique:
received: 07 08 2018
revised: 17 12 2018
accepted: 17 12 2018
pubmed: 24 12 2018
medline: 21 12 2019
entrez: 22 12 2018
Statut: ppublish

Résumé

Sun radiation is indispensable to our health, however, a long term and high exposure could lead to erythema, premature skin aging and promotion of skin tumors. An underlying pathomechanism is the formation of free radicals. First, reactive oxygen species (*OH, *O

Identifiants

DOI: 10.1016/j.freeradbiomed.2018.12.022 PMID: 30576782
pubmed: 30576782
pii: S0891-5849(18)31373-X
doi: 10.1016/j.freeradbiomed.2018.12.022
pii:
doi:

Substances chimiques

Cyclic N-Oxides 0
Free Radicals 0
Spin Labels 0
5,5-dimethyl-1-pyrroline-1-oxide 7170JZ1QF3
Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

299-308

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Stephanie Albrecht (S)

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: stephanie.albrecht@charite.de.

Anja Elpelt (A)

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charitéplatz 1, 10117 Berlin, Germany; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany. Electronic address: anja.elpelt@charite.de.

Ceyda Kasim (C)

Institute of Biotechnology, Technische Universität Berlin, Ackerstr. 76, 13355 Berlin Germany.

Carina Reble (C)

Courage + Khazaka Electronic GmbH, Mathias-Brüggen-Str. 91, 50829 Köln, Germany. Electronic address: creble@courage-khazaka.de.

Lars Mundhenk (L)

Institute of Veterinary Pathology, Freie Universität Berlin, Robert-von-Ostertag-Str. 15, 14163 Berlin, Germany. Electronic address: lars.mundhenk@fu-berlin.de.

Hannah Pischon (H)

Institute of Veterinary Pathology, Freie Universität Berlin, Robert-von-Ostertag-Str. 15, 14163 Berlin, Germany. Electronic address: hannah.pischon@fu-berlin.de.

Sarah Hedtrich (S)

Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany. Electronic address: sarah.hedtrich@fu-berlin.de.

Christian Witzel (C)

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: christian.witzel@charite.de.

Jürgen Lademann (J)

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: juergen.lademann@charite.de.

Leonhard Zastrow (L)

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charitéplatz 1, 10117 Berlin, Germany.

Ingeborg Beckers (I)

Beuth University of Applied Sciences Berlin, Luxemburger Straße 10, 3353 Berlin, Germany. Electronic address: beckers@beuth-hochschule.de.

Martina C Meinke (MC)

Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: martina.meinke@charite.de.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Quantification and characterization of radical...
questionsmedicales.fr › Composés hétérocycliques › Oxydes hétérocycliques › N-oxydes cycliques › Quantification and characterization of radical...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Hygiène radiologique › Dose de rayonnement › Relation dose-effet des rayonnements › Quantification and characterization of radical...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Spectroscopie de résonance de spin électronique › Quantification and characterization of radical...
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Quantification and characterization of radical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Quantification and characterization of radical...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Traitement d'image par ordinateur › Imagerie tridimensionnelle › Quantification and characterization of radical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Quantification and characterization of radical...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Quantification and characterization of radical...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Quantification and characterization of radical...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › Quantification and characterization of radical...
questionsmedicales.fr › Techniques d'investigation › Radiométrie › Quantification and characterization of radical...
questionsmedicales.fr › Système tégumentaire › Peau › Quantification and characterization of radical...
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Marqueurs de spin › Quantification and characterization of radical...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Lumière du soleil › Quantification and characterization of radical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Quantification and characterization of radical...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de culture de tissus › Quantification and characterization of radical...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Lumière du soleil › Rayons ultraviolets › Quantification and characterization of radical...