Interaction of merozoite surface protein 2 with lipid membranes.

Antigens, Protozoan / chemistry Merozoites / chemistry Plasmodium falciparum / chemistry Protozoan Proteins / chemistry Unilamellar Liposomes / chemistry
aggregation amyloid fibril membrane disruption membrane interaction merozoite surface protein 2

Journal

FEBS letters
ISSN: 1873-3468
Titre abrégé: FEBS Lett
Pays: England
ID NLM: 0155157

Informations de publication

Date de publication:
02 2019
Historique:
received: 19 10 2018
revised: 26 11 2018
accepted: 16 12 2018
pubmed: 28 12 2018
medline: 7 8 2019
entrez: 28 12 2018
Statut: ppublish

Résumé

Merozoite surface protein 2 (MSP2) is a potential vaccine candidate against malaria, although its functional role is yet to be elucidated. Previous studies showed that MSP2 can interact with membranes, which may facilitate merozoite invasion into the host cell. The N-terminal 25 residues of MSP2 (MSP2

Identifiants

DOI: 10.1002/1873-3468.13320 PMID: 30588612
pubmed: 30588612
doi: 10.1002/1873-3468.13320
doi:

Substances chimiques

Antigens, Protozoan 0
Protozoan Proteins 0
Unilamellar Liposomes 0
merozoite surface protein 2, Plasmodium 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Pagination

288-295

Subventions

Organisme : Medical Research Council (NHMRC)
ID : 1125788
Pays : International

Informations de copyright

© 2018 Federation of European Biochemical Societies.

Auteurs

Chenghui Lu (C)

School of Life Sciences, Anhui University, Hefei, China.
Anhui Provincial Engineering Technology Research Center of Microorganisms and Biocatalysis, Hefei, China.

Xue Zheng (X)

School of Life Sciences, Anhui University, Hefei, China.
Anhui Provincial Engineering Technology Research Center of Microorganisms and Biocatalysis, Hefei, China.

Wei Zhang (W)

School of Life Sciences, Anhui University, Hefei, China.
Anhui Provincial Engineering Technology Research Center of Microorganisms and Biocatalysis, Hefei, China.

Hongxin Zhao (H)

High Magnetic Field Laboratory, Key Laboratory of Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.

Christopher A MacRaild (CA)

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.

Raymond S Norton (RS)

Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.

Yonglong Zhuang (Y)

Modern Experimental Technology Center, Anhui University, Hefei, China.

Junfeng Wang (J)

High Magnetic Field Laboratory, Key Laboratory of Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.
Institute of Physical Science and Information Technology, Anhui University, Hefei, China.

Xuecheng Zhang (X)

School of Life Sciences, Anhui University, Hefei, China.
Anhui Provincial Engineering Technology Research Center of Microorganisms and Biocatalysis, Hefei, China.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de protozoaire › Interaction of merozoite surface protein 2...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Morphogenèse › Métamorphose biologique › Étapes du cycle de vie › Schizontes › Mérozoïtes › Interaction of merozoite surface protein 2...
questionsmedicales.fr › Eucaryotes › Alveolata › Apicomplexa › Haemosporida › Plasmodium › Plasmodium falciparum › Interaction of merozoite surface protein 2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de protozoaire › Interaction of merozoite surface protein 2...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Liposomes › Liposomes unilamellaires › Interaction of merozoite surface protein 2...