Levamisole for children with nephrotic syndrome: new evidence for the use of an "old" drug.

Child Glucocorticoids Humans Immunosuppressive Agents Levamisole Mycophenolic Acid Nephrotic Syndrome Recurrence

Journal

Kidney international
ISSN: 1523-1755
Titre abrégé: Kidney Int
Pays: United States
ID NLM: 0323470

Informations de publication

Date de publication:
01 2019
Historique:
received: 25 09 2018
accepted: 02 10 2018
entrez: 5 1 2019
pubmed: 5 1 2019
medline: 2 4 2019
Statut: ppublish

Résumé

In the current issue of Kidney International, Sinha et al. report results of a randomized controlled trial comparing levamisole and mycophenolate mofetil for the second-line treatment of children with frequent relapses of nephrotic syndrome. This study suggests that these two agents may both be safe and effective. The present commentary addresses strengths and limitations of this important study.

Identifiants

DOI: 10.1016/j.kint.2018.10.008 PMID: 30606425
pubmed: 30606425
pii: S0085-2538(18)30750-6
doi: 10.1016/j.kint.2018.10.008
pii:
doi:

Substances chimiques

Glucocorticoids 0
Immunosuppressive Agents 0
Levamisole 2880D3468G
Mycophenolic Acid HU9DX48N0T

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

25-28

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2018 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

Auteurs

Marina Vivarelli (M)

Division of Nephrology, Department of Pediatric Subspecialties, Bambino Gesù Children's Hospital IRCCS, Rome, Italy. Electronic address: marina.vivarelli@opbg.net.

Francesco Emma (F)

Division of Nephrology, Department of Pediatric Subspecialties, Bambino Gesù Children's Hospital IRCCS, Rome, Italy. Electronic address: francesco.emma@opbg.net.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Levamisole for children with nephrotic...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Hormones › Glucocorticoïdes › Levamisole for children with nephrotic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Levamisole for children with nephrotic...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Immunosuppresseurs › Levamisole for children with nephrotic...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Thiazoles › Lévamisole › Levamisole for children with nephrotic...
questionsmedicales.fr › Lipides › Acides gras › Acide mycophénolique › Levamisole for children with nephrotic...
questionsmedicales.fr › Maladies urogénitales › Maladies urologiques › Maladies du rein › Néphrose › Syndrome néphrotique › Levamisole for children with nephrotic...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Récidive › Levamisole for children with nephrotic...