Hepatic encephalopathy 2018: A clinical practice guideline by the Italian Association for the Study of the Liver (AISF).


Journal

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
ISSN: 1878-3562
Titre abrégé: Dig Liver Dis
Pays: Netherlands
ID NLM: 100958385

Informations de publication

Date de publication:
02 2019
Historique:
received: 29 10 2018
revised: 27 11 2018
accepted: 28 11 2018
pubmed: 5 1 2019
medline: 14 6 2019
entrez: 5 1 2019
Statut: ppublish

Résumé

Hepatic encephalopathy (HE) is a common, worrisome and sometimes difficult to manage complication of end-stage liver disease. HE is often recurrent, requiring multiple hospital admissions. It can have serious implications in terms of a patient's ability to perform complex tasks (for example driving), their earning capacity, their social and family roles. This guideline reviews current knowledge on HE definition, pathophysiology, diagnosis and treatment, both by general principles and by way of a summary of available drugs and treatment strategies. The quality of the published, pertinent evidence is graded, and practical recommendations are made. Where possible, these are placed within the Italian health service context, with reference to local diagnosis and management experience.

Identifiants

pubmed: 30606696
pii: S1590-8658(18)31274-X
doi: 10.1016/j.dld.2018.11.035
pii:
doi:

Types de publication

Journal Article Practice Guideline

Langues

eng

Sous-ensembles de citation

IM

Pagination

190-205

Informations de copyright

Copyright © 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Auteurs

Sara Montagnese (S)

Department of Medicine, University of Padova, Italy. Electronic address: sara.montagnese@unipd.it.

Francesco Paolo Russo (FP)

Department of Surgery, Oncology and Gastroenterology, University of Padova, Italy.

Piero Amodio (P)

Department of Medicine, University of Padova, Italy.

Patrizia Burra (P)

Department of Surgery, Oncology and Gastroenterology, University of Padova, Italy.

Antonio Gasbarrini (A)

Division of Internal Medicine, Gastroenterology and Hepatology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

Carmela Loguercio (C)

Department of Clinical and Experimental Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Giulio Marchesini (G)

Unit of Metabolic Diseases & Clinical Dietetics, Department of Medical and Surgical Sciences, University of Bologna, Italy.

Manuela Merli (M)

Division of Gastroenterology, Department of Clinical Medicine, La Sapienza University of Rome, Italy.

Francesca Romana Ponziani (FR)

Division of Internal Medicine, Gastroenterology and Hepatology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

Oliviero Riggio (O)

Division of Gastroenterology, Department of Clinical Medicine, La Sapienza University of Rome, Italy.

Carmelo Scarpignato (C)

Clinical Pharmacology & Digestive Pathophysiology Unit, Department of Clinical & Experimental Medicine, University of Parma, Italy.

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Classifications MeSH