questionsmedicales.fr
Maladies de l'appareil digestif
Maladies du foie
Insuffisance hépatique
Défaillance hépatique
Maladie du foie en phase terminale
Maladie du foie en phase terminale : Questions médicales fréquentes
Diagnostic
5
Maladie du foie
Biopsie hépatique
Ascite
Encéphalopathie hépatique
Échographie
Tomodensitométrie
Biopsie hépatique
Lésions hépatiques
Symptômes
5
Encéphalopathie hépatique
Troubles de la conscience
Ascite
Pression intra-abdominale
Saignement
Varices œsophagiennes
Démangeaisons
Éruption cutanée
Prévention
5
Dépistage
Maladies hépatiques
Infections hépatiques
Vaccination
Traitements
5
Transplantation hépatique
Médicaments
Transplantation hépatique
Maladie terminale
Médicaments
Complications
Encéphalopathie hépatique
Lactulose
Complications
5
Insuffisance hépatique
Cancer du foie
Insuffisance hépatique
Fonctions hépatiques
Varices œsophagiennes
Saignements
Suivi médical
Traitement précoce
Facteurs de risque
5
Diabète
Maladies hépatiques
Toxines
Produits chimiques
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Maladie du foie en phase terminale : Questions médicales les plus fréquentes",
"headline": "Maladie du foie en phase terminale : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Maladie du foie en phase terminale : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-03-18",
"dateModified": "2025-03-13",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Maladie du foie en phase terminale"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Défaillance hépatique",
"url": "https://questionsmedicales.fr/mesh/D017093",
"about": {
"@type": "MedicalCondition",
"name": "Défaillance hépatique",
"code": {
"@type": "MedicalCode",
"code": "D017093",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C06.552.308.500"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Maladie du foie en phase terminale",
"alternateName": "End Stage Liver Disease",
"code": {
"@type": "MedicalCode",
"code": "D058625",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "None None",
"url": "https://questionsmedicales.fr/author/None%20None",
"affiliation": {
"@type": "Organization",
"name": ""
}
},
{
"@type": "Person",
"name": "Rodrigo M Florentino",
"url": "https://questionsmedicales.fr/author/Rodrigo%20M%20Florentino",
"affiliation": {
"@type": "Organization",
"name": "Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA."
}
},
{
"@type": "Person",
"name": "Barret Rush",
"url": "https://questionsmedicales.fr/author/Barret%20Rush",
"affiliation": {
"@type": "Organization",
"name": "Division of Critical Care Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada bar890@mail.harvard.edu."
}
},
{
"@type": "Person",
"name": "Mayur Brahmania",
"url": "https://questionsmedicales.fr/author/Mayur%20Brahmania",
"affiliation": {
"@type": "Organization",
"name": "Division of Gastroenterology, Department of Medicine, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada."
}
},
{
"@type": "Person",
"name": "Amy W Johnson",
"url": "https://questionsmedicales.fr/author/Amy%20W%20Johnson",
"affiliation": {
"@type": "Organization",
"name": "Division of General Internal Medicine & Geriatrics, Indiana University School of Medicine, Indianapolis, IN, USA."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Mortality in patients with end-stage liver disease above model for end-stage liver disease 3.0 of 40.",
"datePublished": "2023-02-17",
"url": "https://questionsmedicales.fr/article/36052665",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/hep.32770"
}
},
{
"@type": "ScholarlyArticle",
"name": "Chronotropic incompetence in end-stage liver disease.",
"datePublished": "2022-08-01",
"url": "https://questionsmedicales.fr/article/35913923",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1371/journal.pone.0270784"
}
},
{
"@type": "ScholarlyArticle",
"name": "Model for End-Stage Liver Disease/Pediatric End-Stage Liver Disease exception policy and outcomes in pediatric patients with hepatopulmonary syndrome requiring liver transplantation.",
"datePublished": "2023-01-17",
"url": "https://questionsmedicales.fr/article/35876731",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/lt.26548"
}
},
{
"@type": "ScholarlyArticle",
"name": "The Model for End-stage Liver Disease 3.0 is not superior to the Model for End-stage Liver Disease-Na in predicting survival: A retrospective cohort study.",
"datePublished": "2023-09-22",
"url": "https://questionsmedicales.fr/article/37738412",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1097/HC9.0000000000000250"
}
},
{
"@type": "ScholarlyArticle",
"name": "A comprehensive review of coronary artery disease in patients with end-stage liver disease.",
"datePublished": "2022-05-21",
"url": "https://questionsmedicales.fr/article/35665672",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.trre.2022.100709"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Maladies de l'appareil digestif",
"item": "https://questionsmedicales.fr/mesh/D004066"
},
{
"@type": "ListItem",
"position": 3,
"name": "Maladies du foie",
"item": "https://questionsmedicales.fr/mesh/D008107"
},
{
"@type": "ListItem",
"position": 4,
"name": "Insuffisance hépatique",
"item": "https://questionsmedicales.fr/mesh/D048550"
},
{
"@type": "ListItem",
"position": 5,
"name": "Défaillance hépatique",
"item": "https://questionsmedicales.fr/mesh/D017093"
},
{
"@type": "ListItem",
"position": 6,
"name": "Maladie du foie en phase terminale",
"item": "https://questionsmedicales.fr/mesh/D058625"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Maladie du foie en phase terminale - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Maladie du foie en phase terminale",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-04-28",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Maladie du foie en phase terminale",
"description": "Comment diagnostiquer une maladie du foie en phase terminale ?\nQuels tests sanguins sont utilisés pour le diagnostic ?\nQuels signes cliniques indiquent une phase terminale ?\nL'imagerie est-elle utile pour le diagnostic ?\nQuelle est l'importance de la biopsie hépatique ?",
"url": "https://questionsmedicales.fr/mesh/D058625#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Maladie du foie en phase terminale",
"description": "Quels sont les symptômes courants de cette maladie ?\nComment se manifeste l'encéphalopathie hépatique ?\nQu'est-ce que l'ascite ?\nLes saignements sont-ils fréquents ?\nQuels changements cutanés peuvent apparaître ?",
"url": "https://questionsmedicales.fr/mesh/D058625#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Maladie du foie en phase terminale",
"description": "Comment prévenir la maladie du foie ?\nLe dépistage est-il important ?\nQuels aliments sont à éviter ?\nL'exercice physique aide-t-il ?\nLes infections hépatiques peuvent-elles être évitées ?",
"url": "https://questionsmedicales.fr/mesh/D058625#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Maladie du foie en phase terminale",
"description": "Quels traitements sont disponibles pour cette maladie ?\nComment gérer l'ascite ?\nQuel rôle joue la transplantation hépatique ?\nLes médicaments peuvent-ils aider ?\nComment traiter l'encéphalopathie hépatique ?",
"url": "https://questionsmedicales.fr/mesh/D058625#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Maladie du foie en phase terminale",
"description": "Quelles sont les complications possibles ?\nComment l'insuffisance hépatique se manifeste-t-elle ?\nLes varices œsophagiennes sont-elles dangereuses ?\nLe cancer du foie est-il fréquent ?\nComment prévenir les complications ?",
"url": "https://questionsmedicales.fr/mesh/D058625#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Maladie du foie en phase terminale",
"description": "Quels sont les principaux facteurs de risque ?\nL'hépatite C augmente-t-elle le risque ?\nLe diabète est-il un facteur de risque ?\nL'exposition à des toxines est-elle un risque ?\nLe sexe influence-t-il le risque ?",
"url": "https://questionsmedicales.fr/mesh/D058625#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une maladie du foie en phase terminale ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur des tests sanguins, échographies et biopsies hépatiques."
}
},
{
"@type": "Question",
"name": "Quels tests sanguins sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent les transaminases, la bilirubine et l'albumine."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques indiquent une phase terminale ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes incluent l'ascite, l'encéphalopathie hépatique et la jaunisse."
}
},
{
"@type": "Question",
"name": "L'imagerie est-elle utile pour le diagnostic ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'échographie et le scanner peuvent évaluer l'état du foie."
}
},
{
"@type": "Question",
"name": "Quelle est l'importance de la biopsie hépatique ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet d'évaluer la gravité des lésions hépatiques et de confirmer le diagnostic."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes courants de cette maladie ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent fatigue, démangeaisons, jaunisse et gonflement abdominal."
}
},
{
"@type": "Question",
"name": "Comment se manifeste l'encéphalopathie hépatique ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle se manifeste par des troubles de la conscience, confusion et changements de comportement."
}
},
{
"@type": "Question",
"name": "Qu'est-ce que l'ascite ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'ascite est l'accumulation de liquide dans l'abdomen, causée par une pression accrue."
}
},
{
"@type": "Question",
"name": "Les saignements sont-ils fréquents ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les saignements peuvent survenir en raison de varices œsophagiennes."
}
},
{
"@type": "Question",
"name": "Quels changements cutanés peuvent apparaître ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des démangeaisons et des éruptions cutanées peuvent survenir à cause de l'accumulation de toxines."
}
},
{
"@type": "Question",
"name": "Comment prévenir la maladie du foie ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évitez l'alcool, maintenez un poids santé et vaccinez-vous contre l'hépatite."
}
},
{
"@type": "Question",
"name": "Le dépistage est-il important ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage régulier peut aider à détecter les maladies hépatiques précocement."
}
},
{
"@type": "Question",
"name": "Quels aliments sont à éviter ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évitez les aliments gras, salés et riches en sucre pour protéger le foie."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier aide à maintenir un poids santé et à réduire le risque."
}
},
{
"@type": "Question",
"name": "Les infections hépatiques peuvent-elles être évitées ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, en évitant les comportements à risque et en se faisant vacciner."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour cette maladie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des médicaments, des soins de soutien et la transplantation hépatique."
}
},
{
"@type": "Question",
"name": "Comment gérer l'ascite ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'ascite peut être traitée par des diurétiques ou par une paracentèse pour retirer le liquide."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la transplantation hépatique ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La transplantation est souvent le seul traitement curatif pour la maladie en phase terminale."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent soulager les symptômes et prévenir les complications."
}
},
{
"@type": "Question",
"name": "Comment traiter l'encéphalopathie hépatique ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est traitée par des médicaments comme la lactulose et des modifications diététiques."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent l'insuffisance hépatique, les infections et le cancer du foie."
}
},
{
"@type": "Question",
"name": "Comment l'insuffisance hépatique se manifeste-t-elle ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle se manifeste par une défaillance des fonctions hépatiques et des symptômes graves."
}
},
{
"@type": "Question",
"name": "Les varices œsophagiennes sont-elles dangereuses ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent provoquer des saignements potentiellement mortels."
}
},
{
"@type": "Question",
"name": "Le cancer du foie est-il fréquent ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il est plus fréquent chez les personnes atteintes de cirrhose ou d'hépatite chronique."
}
},
{
"@type": "Question",
"name": "Comment prévenir les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi médical régulier et un traitement précoce des maladies hépatiques sont essentiels."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'alcoolisme, l'obésité, l'hépatite virale et le diabète."
}
},
{
"@type": "Question",
"name": "L'hépatite C augmente-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'hépatite C est un facteur de risque majeur pour la cirrhose et le cancer du foie."
}
},
{
"@type": "Question",
"name": "Le diabète est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète peut aggraver les maladies hépatiques et augmenter le risque de complications."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines est-elle un risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des produits chimiques toxiques peut endommager le foie."
}
},
{
"@type": "Question",
"name": "Le sexe influence-t-il le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains facteurs de risque peuvent varier selon le sexe, affectant la prévalence."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 13/03/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Publications dans "Maladie du foie en phase terminale" :
3 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Maladie du foie en phase terminale" :
3 publications dans cette catégorie
Affiliations :
Division of Critical Care Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada bar890@mail.harvard.edu.
Publications dans "Maladie du foie en phase terminale" :
3 publications dans cette catégorie
Affiliations :
Division of Gastroenterology, Department of Medicine, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada.
Publications dans "Maladie du foie en phase terminale" :
3 publications dans cette catégorie
Affiliations :
Division of General Internal Medicine & Geriatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Division of Gastroenterology and Hepatology, Department of Medicine , Stanford University School of Medicine , Redwood City , California , USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Division of Gastroenterology and Hepatology, Department of Medicine , Stanford University School of Medicine , Redwood City , California , USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Head of Division, Division of Gastroenterology, Hepatology & Nutrition, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
King Faisal Specialist Hospital & Research Center, Organ Transplant Center of Excellence, Riyadh 11564, Saudi Arabia.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Department of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Division of Pulmonary and Critical Care MedicineMayo ClinicRochesterMinnesotaUSA.
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Publications dans "Maladie du foie en phase terminale" :
2 publications dans cette catégorie
Affiliations :
Centre for Heart Lung Innovation (HLI), University of British Columbia, Vancouver, British Columbia, Canada.
Division of Critical Care Medicine, University of British Columbia, Vancouver, Canada.
Publications dans "Maladie du foie en phase terminale" :
Since the implementation of the model for end-stage liver disease (MELD) score to determine waitlist priority for liver transplant (LT) in 2002, the score has been capped at 40. Recently, the MELD 3.0...
Adult waitlist registrations for LT from January 2016 to December 2021 were identified in the registry data from the Organ Procurement and Transplant Network. All MELD 3.0 scores were calculated at re...
MELD 3.0 scores beyond 40 are associated with increasing waitlist mortality without adversely affecting posttransplant outcome. Uncapping the MELD score in waitlist candidates may lead to greater surv...
Cirrhosis causes alterations in the cardiovascular and autonomic nervous systems and leads to cirrhotic cardiomyopathy (CCM). CCM is defined as cardiac dysfunction characterized by an impaired systoli...
The analysis included 160 end-stage liver disease (ESLD) patients who underwent a cardiac exercise stress test prior to the orthotopic liver transplantation. CI was defined as the inability to achieve...
In the analyzed population, 68.8% of patients met the criteria for CI. CI was more frequent in the more severe ESLD (with a higher MELD score and in a higher Child-Pugh class). In comparison to the vi...
The prevalence of CI is higher among liver transplant candidates than previously described. The altered chronotropic response may differ in regard to the severity of liver disease correlating with bot...
Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End-Stage Liver Disease (MELD)/Pediatri...
The Model for End-stage Liver Disease (MELD) 3.0 yields high prognostic performance for patients with end-stage liver disease (ESLD). However, its prognostic performance for patients with alcohol-rela...
Patients hospitalized with ARLD in one institution between 2015 and 2018 were retrospectively included and followed up for 12 months. The original MELD, MELD-Na, MELD 3.0, and modified Maddrey discrim...
Among the 576 patients included in our analysis, 209 patients had alcoholic hepatitis (AH). By the 1-year follow-up, 14.8% (84/567) of all the patients and 23.4% (49/209) of those with AH had died. Ov...
The MELD 3.0 was not superior to the original MELD or the MELD-Na in predicting the mortality of patients with ARLD....
The prevalence of coronary artery disease has increased in patients with end stage liver disease. In the near future, non-alcoholic steatohepatitis is expected to be the leading cause of end stage liv...
Ischemia-reperfusion injury (IRI) has thus far been considered as an inevitable component of organ transplantation, compromising outcomes, and limiting organ availability. Ischemia-free organ transpla...
In this randomized-controlled clinical trial, recipients of livers from donors after brain death were randomly assigned to receive either an ischemia-free or a 'conventional' transplant. The primary e...
Out of 68 randomized patients, 65 underwent transplants and were included in the analysis. 32 patients received ischemia-free liver transplantation (IFLT), and 33 received conventional liver transplan...
Among patients with end-stage liver disease, IFLT significantly reduced complications related to IRI compared to a conventional approach....
chictr.org. ChiCTR1900021158....
Ischemia-reperfusion injury has thus far been considered as an inevitable event in organ transplantation, compromising outcomes and limiting organ availability. Ischemia-free liver transplantation is ...
Hepatocellular carcinoma (HCC) is a major health problem worldwide, especially for patients who are suffering from end-stage liver disease (ESLD). The ESLD is considered a great challenge for clinicia...
Liver transplantation is a high-risk surgery associated with important perioperative bleeding and transfusion needs. Uncertainties remain on the association between preoperative fibrinogen level and b...
We conducted a cohort study that included all consecutive adult patients undergoing a liver transplantation for end-stage liver disease in 1 center. We analyzed the association between the preoperativ...
We included 613 patients. We observed that a lower fibrinogen level was associated with a higher intraoperative blood loss, a higher estimated perioperative blood loss and a higher risk of intraoperat...
This study suggests that a lower fibrinogen level is associated with bleeding in liver transplantation. The present results may help improving the selection of patients for further studies on preopera...
Malnutrition is ubiquitous in cirrhotic patients presenting for liver transplant (LT). Providing an appropriate energy prescription is fundamental to effective nutrition therapy. We aimed to compare m...
Patients with end-stage liver disease (ESLD) commonly experience pain and other symptoms that result in a poor quality of life. Few studies have examined opioid usage, adverse events (AEs), and other ...
This study aimed to compare outcomes in ESLD patients who received opioids to those who did not and to determine risk factors for AEs....
This was a retrospective case-cohort study of 270 hospitalized patients with ESLD that used administrative and clinical data from the electronic medical record....
Two-thirds of patients with ESLD admitted during the study period received at least one opioid analgesic. Patients who received opioids presented with a greater number of liver related complications a...
Opioid administration was not an independent risk factor for the number of AEs in hospitalized patients with ESLD, whereas anxiety and more liver-related complications increased AE risk. Our findings ...