Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression.


Journal

Molecular cancer research : MCR
ISSN: 1557-3125
Titre abrégé: Mol Cancer Res
Pays: United States
ID NLM: 101150042

Informations de publication

Date de publication:
04 2019
Historique:
received: 13 06 2018
revised: 26 09 2018
accepted: 21 12 2018
pubmed: 6 1 2019
medline: 10 1 2020
entrez: 6 1 2019
Statut: ppublish

Résumé

Granulocytic myeloid infiltration and resultant enhanced neutrophil elastase (NE) activity is associated with poor outcomes in numerous malignancies. We recently showed that NE expression and activity from infiltrating myeloid cells was high in human prostate cancer xenografts and mouse

Identifiants

pubmed: 30610107
pii: 1541-7786.MCR-18-0638
doi: 10.1158/1541-7786.MCR-18-0638
pmc: PMC6445715
mid: NIHMS1517648
doi:

Substances chimiques

Histones 0
RNA, Messenger 0
Serpins 0
SERPINB1 protein, human 147416-07-7
EZH2 protein, human EC 2.1.1.43
Enhancer of Zeste Homolog 2 Protein EC 2.1.1.43

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

845-859

Subventions

Organisme : NCI NIH HHS
ID : F30 CA203517
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA193583
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM101709
Pays : United States

Informations de copyright

©2019 American Association for Cancer Research.

Références

Oncotarget. 2016 Mar 1;7(9):10117-32
pubmed: 26799424
PLoS One. 2012;7(12):e51136
pubmed: 23251436
Respir Res. 2008 Aug 12;9:60
pubmed: 18699987
Nucleic Acids Res. 2015 Jan;43(Database issue):D856-61
pubmed: 25398901
J Biol Chem. 2002 Nov 1;277(44):42028-33
pubmed: 12189154
JAMA. 2017 Jun 27;317(24):2532-2542
pubmed: 28655021
J Immunol. 2012 Nov 1;189(9):4574-81
pubmed: 23002442
Oncol Rep. 2012 Jan;27(1):238-45
pubmed: 21993616
Prostate. 2015 Oct;75(14):1586-600
pubmed: 26074449
BMC Cancer. 2007 Apr 12;7:64
pubmed: 17430594
J Clin Invest. 2015 Sep;125(9):3356-64
pubmed: 26168215
Cell. 2011 Mar 4;144(5):646-74
pubmed: 21376230
Biomark Cancer. 2016 May 05;8(Suppl 2):15-33
pubmed: 27168728
J Investig Med. 2000 Sep;48(5):359-66
pubmed: 10979241
Cancer Res. 2004 Sep 1;64(17):5963-72
pubmed: 15342375
J Clin Invest. 2009 Jun;119(6):1420-8
pubmed: 19487818
Hum Genomics. 2013 Oct 30;7:22
pubmed: 24172014
Nature. 2014 Nov 6;515(7525):134-7
pubmed: 25156255
Cancer Cell. 2010 Jul 13;18(1):11-22
pubmed: 20579941
Endocrinology. 2017 Sep 1;158(9):2944-2954
pubmed: 28666321
Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20111-6
pubmed: 24282295
Cancer Discov. 2016 Jan;6(1):80-95
pubmed: 26701088
Nat Rev Drug Discov. 2006 Sep;5(9):785-99
pubmed: 16955069
Mol Cancer Res. 2017 Sep;15(9):1138-1152
pubmed: 28512253
J Leukoc Biol. 2011 Jul;90(1):21-9
pubmed: 21248149
Endocr Relat Cancer. 2012 Oct 30;19(6):R187-204
pubmed: 22930558
Breast Cancer Res. 2013 Jan 15;15(1):R3
pubmed: 23320734
Eur Respir J. 2011 May;37(5):1083-90
pubmed: 20817705
J Dermatol. 2014 May;41(5):393-8
pubmed: 24750314
Protein Cell. 2013 May;4(5):331-41
pubmed: 23636686
Mutat Res. 2008 Dec 1;647(1-2):21-9
pubmed: 18723033
Am J Pathol. 2013 Mar;182(3):975-91
pubmed: 23313138
Oncogene. 2015 Jul;34(27):3556-67
pubmed: 25195861
Biol Reprod. 2015 Sep;93(3):65
pubmed: 26203177
Cell. 2008 Mar 7;132(5):818-31
pubmed: 18329368
Nat Med. 2018 Feb;24(2):165-175
pubmed: 29309058
Dis Markers. 2016;2016:4358292
pubmed: 27594734
Cell Metab. 2016 Jan 12;23(1):194-205
pubmed: 26701651
Clin Cancer Res. 2009 Sep 15;15(18):5794-802
pubmed: 19737960
Front Oncol. 2015 Jul 08;5:128
pubmed: 26217583
Methods Enzymol. 2011;499:135-48
pubmed: 21683252
Cancer Cell. 2005 Nov;8(5):393-406
pubmed: 16286247
Steroids. 2018 May;133:96-101
pubmed: 29155217
Brain Res. 2015 Mar 10;1600:59-69
pubmed: 24968089
Mol Cell Biol. 2014 Jun;34(11):2017-28
pubmed: 24662052
Genome Res. 2011 Jul;21(7):1017-27
pubmed: 21521786
Semin Cell Dev Biol. 2017 Feb;62:178-186
pubmed: 27422329
Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1238-60
pubmed: 26921821
Prostate. 2015 Dec;75(16):1831-43
pubmed: 26332574
Clin Cancer Res. 2015 Aug 15;21(16):3771-82
pubmed: 25967142
Endocr Relat Cancer. 2016 Apr;23(4):265-80
pubmed: 26880751
J Mol Histol. 2014 Feb;45(1):59-68
pubmed: 24105272
Bioresour Technol. 2015 Sep;192:636-45
pubmed: 26094188

Auteurs

Irina Lerman (I)

Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center, Rochester, New York.

Xiaoting Ma (X)

Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center, Rochester, New York.

Christina Seger (C)

Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center, Rochester, New York.

Aerken Maolake (A)

Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York.

Maria de la Luz Garcia-Hernandez (ML)

Division of Allergy/Immunology and Rheumatology, Department of Medicine, University of Rochester Medical Center, Rochester, New York.

Javier Rangel-Moreno (J)

Division of Allergy/Immunology and Rheumatology, Department of Medicine, University of Rochester Medical Center, Rochester, New York.

Jessica Ackerman (J)

Department of Pathology, University of Rochester Medical Center, Rochester, New York.

Kent L Nastiuk (KL)

Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York.

Martha Susiarjo (M)

Department of Environmental Medicine, University of Rochester Medical Center, Rochester, New York.

Stephen R Hammes (SR)

Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center, Rochester, New York. stephen_hammes@urmc.rochester.edu.

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Classifications MeSH