Bioactivity of dietary polyphenols: The role of metabolites.
Resveratrol
bioactive metabolites
curcumin
ellagitannins
low oral bioavailability
proanthocyanidins
Journal
Critical reviews in food science and nutrition
ISSN: 1549-7852
Titre abrégé: Crit Rev Food Sci Nutr
Pays: United States
ID NLM: 8914818
Informations de publication
Date de publication:
2020
2020
Historique:
pubmed:
8
1
2019
medline:
1
4
2020
entrez:
8
1
2019
Statut:
ppublish
Résumé
A polyphenol-rich diet protects against chronic pathologies by modulating numerous physiological processes, such as cellular redox potential, enzymatic activity, cell proliferation and signaling transduction pathways. However, polyphenols have a low oral bioavailability mainly due to an extensive biotransformation mediated by phase I and phase II reactions in enterocytes and liver but also by gut microbiota. Despite low oral bioavailability, most polyphenols proved significant biological effects which brought into attention
Identifiants
pubmed: 30614249
doi: 10.1080/10408398.2018.1546669
doi:
Substances chimiques
Polyphenols
0
Resveratrol
Q369O8926L
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM