Nanoconfinement Effects on the Glass Transition and Crystallization Behaviors of Nifedipine.

Crystallization / methods Glass / chemistry Nifedipine / chemistry Temperature Thermodynamics Transition Temperature
amorphous pharmaceutical cold-crystallization glass transition nifedipine polymorphism

Journal

Molecular pharmaceutics
ISSN: 1543-8392
Titre abrégé: Mol Pharm
Pays: United States
ID NLM: 101197791

Informations de publication

Date de publication:
04 02 2019
Historique:
pubmed: 8 1 2019
medline: 19 11 2019
entrez: 8 1 2019
Statut: ppublish

Résumé

The impact of nanoconfinement on the crystallization and glass transition behaviors of nifedipine (NIF) has been investigated using differential scanning calorimetry. Nanoconfinement was provided by imbibing the NIF into a porous medium (controlled pore glass, CPG), and results were compared with the unconfined bulk material. Consistent with previous results from the literature, both glass transition temperature T

Identifiants

DOI: 10.1021/acs.molpharmaceut.8b01172 PMID: 30615456
pubmed: 30615456
doi: 10.1021/acs.molpharmaceut.8b01172
doi:

Substances chimiques

Nifedipine I9ZF7L6G2L

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

856-866

Auteurs

Sixue Cheng (S)

Department of Chemical Engineering, Whitacre College of Engineering , Texas Tech University , Lubbock , Texas 79409-3121 , United States.

Gregory B McKenna (GB)

Department of Chemical Engineering, Whitacre College of Engineering , Texas Tech University , Lubbock , Texas 79409-3121 , United States.
ORCID: 0000-0002-5676-9930

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Cristallisation › Nanoconfinement Effects on the Glass...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Verre › Nanoconfinement Effects on the Glass...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyridines › Dihydropyridines › Nifédipine › Nanoconfinement Effects on the Glass...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Température › Nanoconfinement Effects on the Glass...
questionsmedicales.fr › Phénomènes physiques › Thermodynamique › Nanoconfinement Effects on the Glass...
questionsmedicales.fr › Phénomènes physiques › Thermodynamique › Température de transition › Nanoconfinement Effects on the Glass...