Monte-Carlo simulation of the Siemens Artiste linear accelerator flat 6 MV and flattening-filter-free 7 MV beam line.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2019
Historique:
received: 31 08 2018
accepted: 17 12 2018
entrez: 9 1 2019
pubmed: 9 1 2019
medline: 1 10 2019
Statut: epublish

Résumé

The aim of our work is to provide the up-to-now missing information on the Siemens Artiste FFF 7 MV beam line using a Monte-Carlo model fit to the realistic dosimetric measurements at the linear accelerator in clinical use at our department. The main Siemens Artiste 6MV and FFF 7MV beams were simulated using the Geant4 toolkit. The simulations were compared with the measurements with an ionization chamber in a water phantom to verify the validation of simulation and tuning the primary electron parameters. Hereafter, other parameters such as surface dose, spectrum, electron contamination, symmetry, flatness/unflatness, slope, and characteristic off-axis changes were discussed for both Flat and FFF mode. The mean electron energy for the FFF beam was 8.8 MeV and 7.5 MeV for Flat 6 MV, the spread energy and spot size of the selected Gaussian distribution source were 0.4 MeV and 1mm, respectively. The dose rate of the FFF beam was 2.8 (2.96) times higher than for the flattened beam for a field size of 10×10 (20×20) cm2. The electron contamination has significant contribution to the surface dose especially for the flattened beam. The penumbra, surface dose and the mean energy of photons decrease by removing the flattening filter. Finally, the results show that off-axis changes have no strong effect on the mean energy of FFF beams, while this effect was more considerable for the flattened beam.

Identifiants

pubmed: 30620742
doi: 10.1371/journal.pone.0210069
pii: PONE-D-18-25146
pmc: PMC6324801
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0210069

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Radiat Prot Dosimetry. 2006;119(1-4):506-9
pubmed: 16644964
Rep Pract Oncol Radiother. 2014 Jul 15;19(5):322-31
pubmed: 25184057
Phys Med Biol. 2007 Aug 7;52(15):4449-63
pubmed: 17634643
Med Phys. 2006 Jun;33(6):1738-46
pubmed: 16872081
Rep Pract Oncol Radiother. 2017 May-Jun;22(3):243-250
pubmed: 28479873
Med Phys. 2000 Mar;27(3):499-513
pubmed: 10757602
Med Phys. 1997 Dec;24(12):1960-74
pubmed: 9434979
Phys Med Biol. 2004 Jun 21;49(12):2657-73
pubmed: 15272680
Med Phys. 2002 Dec;29(12):2745-52
pubmed: 12512706
Phys Med Biol. 2003 Nov 7;48(21):R107-64
pubmed: 14653555
J Med Signals Sens. 2013 Jul;3(3):172-9
pubmed: 24672765
Pract Radiat Oncol. 2014 Mar-Apr;4(2):e109-e116
pubmed: 24890356
Radiat Oncol. 2013 May 31;8:133
pubmed: 23725479
Med Phys. 2011 Sep;38(9):5104-18
pubmed: 21978056
Appl Radiat Isot. 2007 Sep;65(9):1029-36
pubmed: 17616465
Phys Med Biol. 2010 Dec 7;55(23):7333-44
pubmed: 21081829
J Appl Clin Med Phys. 2012 Jul 05;13(4):3701
pubmed: 22766941
Radiat Oncol. 2014 Nov 26;9:250
pubmed: 25424536
Med Phys. 2006 Apr;33(4):820-7
pubmed: 16696457
J Appl Clin Med Phys. 2015 May 08;16(3):5219
pubmed: 26103482
Z Med Phys. 2013 Dec;23(4):291-9
pubmed: 23669174
J Appl Clin Med Phys. 2015 Mar 08;16(2):5351
pubmed: 26103202
Med Phys. 2012 May;39(5):2595-602
pubmed: 22559630
Radiat Med. 2007 Aug 1;25(7):315-24
pubmed: 17705000
Med Phys. 2000 Jan;27(1):180-91
pubmed: 10659756
Med Phys. 2017 Jun;44(6):2569-2580
pubmed: 28369978
J Biomed Phys Eng. 2018 Jun 01;8(2):157-166
pubmed: 29951442
Med Phys. 2013 Nov;40(11):112101
pubmed: 24320454
PLoS One. 2013;8(1):e53799
pubmed: 23326510
J Biomed Phys Eng. 2015 Mar 04;5(1):31-8
pubmed: 25973409
Phys Med Biol. 2011 Jul 21;56(14):4355-76
pubmed: 21709343
PLoS One. 2014 Apr 10;9(4):e94371
pubmed: 24722621
Med Phys. 2012 Oct;39(10):6455-64
pubmed: 23039680
Phys Med. 2016 Mar;32(3):474-8
pubmed: 27053450
PLoS One. 2016 Oct 14;11(10):e0164616
pubmed: 27741272
Phys Med. 2014 Nov;30(7):833-7
pubmed: 24947967

Auteurs

Alemeh Sadrollahi (A)

Department of Radiotherapy and Radiation Oncology, Saarland University Medical Center, Homburg, Saarland, Germany.

Frank Nuesken (F)

Department of Radiotherapy and Radiation Oncology, Saarland University Medical Center, Homburg, Saarland, Germany.

Norbert Licht (N)

Department of Radiotherapy and Radiation Oncology, Saarland University Medical Center, Homburg, Saarland, Germany.

Christian Rübe (C)

Department of Radiotherapy and Radiation Oncology, Saarland University Medical Center, Homburg, Saarland, Germany.

Yvonne Dzierma (Y)

Department of Radiotherapy and Radiation Oncology, Saarland University Medical Center, Homburg, Saarland, Germany.

Articles similaires

Humans Middle Aged Female Male Surveys and Questionnaires
Adolescent Child Female Humans Male
Humans Scoliosis Mobile Applications Retrospective Studies Artificial Intelligence

Classifications MeSH