Perioperative magnesium levels in total thyroidectomy and relationship to hypocalcemia.
calcium
hypocalcemia
hypoparathyroidism
magnesium
thyroidectomy
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
07
05
2018
revised:
14
10
2018
accepted:
10
12
2018
pubmed:
11
1
2019
medline:
11
11
2020
entrez:
11
1
2019
Statut:
ppublish
Résumé
We have previously shown an association between hypomagnesemia and hypocalcemia after thyroidectomy. However, little is known regarding the trend in magnesium levels in the days after thyroidectomy. Our objective was to study this trend in magnesium levels after thyroidectomy. Retrospective review of 173 thyroidectomies with analysis of calcium and magnesium levels on postoperative day 1 (POD1) and POD2. Across the whole group, there was a highly significant decline in magnesium levels between preoperative (0.87 ± 0.06 mmol/L), POD1 (0.80 ± 0.07 mmol/L), and POD2 (0.78 ± 0.08 mmol/L) (P < .0001). The magnitudes of the magnesium level declines were significantly higher, and the absolute magnesium levels on POD1 and POD2 significantly lower, in patients developing hypocalcemia (n = 69). Magnesium levels after total thyroidectomy demonstrate a downward trajectory which persists through POD2 and is highly correlated with hypocalcemia. Further study is required to determine if magnesium replacement can alter the course of hypocalcemia in hypocalcemic patients after total thyroidectomy.
Sections du résumé
BACKGROUND
We have previously shown an association between hypomagnesemia and hypocalcemia after thyroidectomy. However, little is known regarding the trend in magnesium levels in the days after thyroidectomy. Our objective was to study this trend in magnesium levels after thyroidectomy.
METHODS
Retrospective review of 173 thyroidectomies with analysis of calcium and magnesium levels on postoperative day 1 (POD1) and POD2.
RESULTS
Across the whole group, there was a highly significant decline in magnesium levels between preoperative (0.87 ± 0.06 mmol/L), POD1 (0.80 ± 0.07 mmol/L), and POD2 (0.78 ± 0.08 mmol/L) (P < .0001). The magnitudes of the magnesium level declines were significantly higher, and the absolute magnesium levels on POD1 and POD2 significantly lower, in patients developing hypocalcemia (n = 69).
CONCLUSION
Magnesium levels after total thyroidectomy demonstrate a downward trajectory which persists through POD2 and is highly correlated with hypocalcemia. Further study is required to determine if magnesium replacement can alter the course of hypocalcemia in hypocalcemic patients after total thyroidectomy.
Substances chimiques
Magnesium
I38ZP9992A
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1713-1718Informations de copyright
© 2019 Wiley Periodicals, Inc.