Mapping of quantitative trait loci for life history traits segregating within common frog populations.
Journal
Heredity
ISSN: 1365-2540
Titre abrégé: Heredity (Edinb)
Pays: England
ID NLM: 0373007
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
16
05
2018
accepted:
12
12
2018
revised:
08
12
2018
pubmed:
12
1
2019
medline:
19
5
2020
entrez:
12
1
2019
Statut:
ppublish
Résumé
The evolution of complex traits is often shaped by adaptive divergence. However, very little is known about the number, effect size, and location of the genomic regions influencing the variation of these traits in natural populations. Based on a dense linkage map of the common frog, Rana temporaria, we have localized, for the first time in amphibians, three significant and nine suggestive quantitative trait loci (QTLs) for metabolic rate, growth rate, development time, and weight at metamorphosis, explaining 5.6-18.9% of the overall phenotypic variation in each trait. We also found a potential pleiotropic QTL between development time and size at metamorphosis that, if confirmed, might underlie the previously reported genetic correlation between these traits. Furthermore, we demonstrate that the genetic variation linked to fitness-related larval traits segregates within Rana temporaria populations. This study provides the first insight into the genomic regions that affect larval life history traits in anurans, providing a valuable resource to delve further into the genomic basis of evolutionary change in amphibians.
Identifiants
pubmed: 30631147
doi: 10.1038/s41437-018-0175-x
pii: 10.1038/s41437-018-0175-x
pmc: PMC6781108
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
800-808Subventions
Organisme : Academy of Finland (Suomen Akatemia)
ID : 266321
Pays : International
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