Effects of blood transfusion on regional tissue oxygenation in preterm newborns are dependent on the degree of anaemia.
anaemia
near-infrared spectroscopy
neonate
tissue oxygenation
Journal
Journal of paediatrics and child health
ISSN: 1440-1754
Titre abrégé: J Paediatr Child Health
Pays: Australia
ID NLM: 9005421
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
07
05
2018
revised:
30
07
2018
accepted:
18
12
2018
pubmed:
12
1
2019
medline:
11
11
2020
entrez:
12
1
2019
Statut:
ppublish
Résumé
Most of the preterm infants are transfused at least once during their stay in the neonatal intensive care unit (NICU). The aims of this study were to demonstrate if packed red blood cell (pRBC) transfusion modulates regional (cerebral, abdominal, renal) tissue oxygen saturation measured by near-infrared spectroscopy (NIRS) and to demonstrate if we can use NIRS to guide transfusion decisions in neonates. A multi-probe NIRS device was applied to anaemic preterm infants of gestational age <33 weeks for 30-60 min before and 24 h after pRBC transfusion. We evaluated the results separately in the subgroup with a pre-transfusion haemoglobin (Hb) < 8 g/dL. Cerebral, abdominal and renal tissue oxygen saturation (rSO There was no significant difference in cerebral rSO The increase in tissue oxygenation in abdominal region after pRBC transfusion suggests decreased tissue oxygenation of intestines during severe anaemia despite cerebral oxygenation being maintained at that particular Hb level. The impact of the increase on renal oxygenation with pRBC transfusion is unclear and might need further investigation. Increase in abdominal rSO
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1209-1213Informations de copyright
© 2019 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).
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