Child-Pugh Classification: Time to Abandon?

Carcinoma, Hepatocellular / classification Decision Support Techniques Humans Liver Cirrhosis / classification Risk Assessment Severity of Illness Index

Journal

Seminars in liver disease
ISSN: 1098-8971
Titre abrégé: Semin Liver Dis
Pays: United States
ID NLM: 8110297

Informations de publication

Date de publication:
Feb 2019
Historique:
pubmed: 12 1 2019
medline: 10 9 2019
entrez: 12 1 2019
Statut: ppublish

Résumé

The Child-Pugh classification is one of the commonest and oldest bedside tools utilized in estimating prognosis in patients with cirrhosis. However, its usage as a risk prediction tool or indeed a decision-making tool should be revisited. In this review, we discuss some inherent issues with the Child-Pugh classification and present a few contexts in which the current usage of Child-Pugh warrants reassessment, elaborating on its utility in acute variceal bleeding, specifically its role in decision-making on early transjugular intrahepatic portosystemic shunt, as well as its use in the context of hepatocellular carcinoma and drug development and dose adjustment.

Identifiants

DOI: 10.1055/s-0038-1676805 PMID: 30634187
pubmed: 30634187
doi: 10.1055/s-0038-1676805
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

96-103

Informations de copyright

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Déclaration de conflit d'intérêts

None

Auteurs

Beverley Kok (B)

Division of Gastroenterology (Liver Unit), University of Alberta, Edmonton, Canada.

Juan G Abraldes (JG)

Division of Gastroenterology (Liver Unit), University of Alberta, Edmonton, Canada.

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Classifications MeSH

questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Carcinome hépatocellulaire › Child-Pugh Classification: Time to Abandon?
questionsmedicales.fr › Sciences de l'information › Informatique › Informatique médicale › Applications de l'informatique médicale › Techniques d'aide à la décision › Child-Pugh Classification: Time to Abandon?
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Child-Pugh Classification: Time to Abandon?
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Cirrhose du foie › Child-Pugh Classification: Time to Abandon?
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Appréciation des risques › Child-Pugh Classification: Time to Abandon?
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Enquêtes et questionnaires › Enquêtes de santé › Indicateurs d'état de santé › Acuité des besoins du patient › Indice de gravité de la maladie › Child-Pugh Classification: Time to Abandon?