Exposure to Different Amounts of Dietary Gluten in Patients with Non-Celiac Gluten Sensitivity (NCGS): An Exploratory Study.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
10 Jan 2019
Historique:
received: 15 10 2018
revised: 06 01 2019
accepted: 07 01 2019
entrez: 13 1 2019
pubmed: 13 1 2019
medline: 29 1 2019
Statut: epublish

Résumé

It is unclear whether patients with non-celiac gluten sensitivity (NCGS) can tolerate gluten. We have evaluated the changes of both gastrointestinal symptoms and quality of life for NCGS patients after the re-introduction of dietary gluten. Twenty-two NCGS patients reporting functional gastroenterological symptoms and on gluten-free diet (GFD) for the previous three weeks were exposed to incremental gluten-containing diets. Three groups were compared at baseline (immediately after 3-weeks on GFD) and immediately after the return of symptomatology: (i) a group tolerating a low-gluten diet (3.5 g gluten/day, week 1,

Identifiants

pubmed: 30634655
pii: nu11010136
doi: 10.3390/nu11010136
pmc: PMC6356445
pii:
doi:

Substances chimiques

Glutens 8002-80-0

Types de publication

Clinical Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Italian Ministry of Health and Lumbardy's Regional Government Authority (Ministero della Salute and Regione Lombardia)
ID : 2011-02348234

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Auteurs

Leda Roncoroni (L)

Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. leda.roncoroni@unimi.it.
Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20133 Milan, Italy. leda.roncoroni@unimi.it.

Karla A Bascuñán (KA)

Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. kbascunan@med.uchile.cl.
Department of Nutrition, School of Medicine, University of Chile, 8380453 Santiago, Chile. kbascunan@med.uchile.cl.

Maurizio Vecchi (M)

Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy. maurizio.vecchi@policlinico.mi.it.
Gastroenterology and Endoscopic Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy. maurizio.vecchi@policlinico.mi.it.

Luisa Doneda (L)

Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20133 Milan, Italy. luisa.doneda@unimi.it.

Maria T Bardella (MT)

Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. mariateresa.bardella@yahoo.com.

Vincenza Lombardo (V)

Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. vicky.l@hotmail.it.

Alice Scricciolo (A)

Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. scricciolo.alice@gmail.com.

Federica Branchi (F)

Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. federica.branchi@gmail.com.

Luca Elli (L)

Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. dottorlucaelli@gmail.com.

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