Is Targeting the Folate Receptor in Ovarian Cancer Coming of Age?


Journal

The oncologist
ISSN: 1549-490X
Titre abrégé: Oncologist
Pays: England
ID NLM: 9607837

Informations de publication

Date de publication:
04 2019
Historique:
received: 30 07 2018
accepted: 21 11 2018
pubmed: 13 1 2019
medline: 21 5 2020
entrez: 13 1 2019
Statut: ppublish

Résumé

Prognosis for women with epithelial ovarian cancer remains poor. One new molecular target in epithelial ovarian cancer is folate receptor alpha (FRα). This commentary discusses the characteristics that contribute to its attractiveness as a candidate for therapeutic intervention.

Identifiants

pubmed: 30635448
pii: theoncologist.2018-0459
doi: 10.1634/theoncologist.2018-0459
pmc: PMC6459241
doi:

Substances chimiques

Antineoplastic Agents 0
Folate Receptor 1 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

425-429

Déclaration de conflit d'intérêts

Disclosures of potential conflicts of interest may be found at the end of this article.

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Auteurs

Michael J Birrer (MJ)

O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA mbirrer@uab.edu.

Ilaria Betella (I)

O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Lainie P Martin (LP)

Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Kathleen N Moore (KN)

Stephenson Oklahoma Cancer Center at the University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

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Classifications MeSH