The
Acinetobacter baumannii
/ genetics
Adenosine Triphosphate
/ chemistry
Anti-Bacterial Agents
/ pharmacology
Bacterial Outer Membrane Proteins
/ metabolism
Biological Transport
Cell Membrane
/ metabolism
Computational Biology
Cryoelectron Microscopy
DNA Transposable Elements
Escherichia coli
/ metabolism
Escherichia coli Proteins
/ metabolism
Genome, Bacterial
Glycerophospholipids
/ metabolism
Hydrolysis
Lipopolysaccharides
/ metabolism
Molecular Conformation
Mutagenesis
Mutation
Phenotype
ABC Transporter
Acinetobacter baumannii
glycerophospholipids
infectious disease
microbiology
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
14 01 2019
14 01 2019
Historique:
received:
17
07
2018
accepted:
11
01
2019
pubmed:
15
1
2019
medline:
19
5
2020
entrez:
15
1
2019
Statut:
epublish
Résumé
The outer membrane (OM) of Gram-negative bacteria serves as a selective permeability barrier that allows entry of essential nutrients while excluding toxic compounds, including antibiotics. The OM is asymmetric and contains an outer leaflet of lipopolysaccharides (LPS) or lipooligosaccharides (LOS) and an inner leaflet of glycerophospholipids (GPL). We screened
Identifiants
pubmed: 30638443
doi: 10.7554/eLife.40171
pii: 40171
pmc: PMC6365058
doi:
pii:
Substances chimiques
Anti-Bacterial Agents
0
Bacterial Outer Membrane Proteins
0
DNA Transposable Elements
0
Escherichia coli Proteins
0
Glycerophospholipids
0
Lipopolysaccharides
0
lipid-linked oligosaccharides
0
Adenosine Triphosphate
8L70Q75FXE
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIGMS NIH HHS
ID : T32 GM008268
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI107775
Pays : United States
Organisme : National Institute of Allergy and Infectious Diseases
ID : U19AI107775
Pays : International
Organisme : NIH HHS
ID : R01GM118396
Pays : United States
Informations de copyright
© 2019, Kamischke et al.
Déclaration de conflit d'intérêts
CK, JF, JB, HK, ZD, AB, JK, SM No competing interests declared
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