Report from the Hand Osteoarthritis Working Group at OMERACT 2018: Update on Core Instrument Set Development.


Journal

The Journal of rheumatology
ISSN: 0315-162X
Titre abrégé: J Rheumatol
Pays: Canada
ID NLM: 7501984

Informations de publication

Date de publication:
09 2019
Historique:
accepted: 14 11 2018
pubmed: 17 1 2019
medline: 21 10 2020
entrez: 17 1 2019
Statut: ppublish

Résumé

To evaluate hand osteoarthritis tools for core instrument set development. For OMERACT 2018, a systematic literature review and advances in instrument validation were presented. Visual analog and numerical rating scales were considered valuable for pain and patient's global assessment, despite heterogeneous phrasing and missing psychometric evidence for some aspects. The Modified Intermittent and Constant Osteoarthritis Pain scale was lacking evidence. The Michigan Hand Outcomes Questionnaire had advantages above other pain/function questionnaires. The Hand Mobility in Scleroderma scale was valid, although responsiveness was questioned. Potential joint activity instruments were evaluated. The development of the core instrument set is progressing, and a research agenda was also developed.

Identifiants

pubmed: 30647176
pii: jrheum.181003
doi: 10.3899/jrheum.181003
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1183-1187

Auteurs

Ruth Wittoek (R)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Féline P B Kroon (FPB)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Burak Kundakci (B)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Abhishek Abhishek (A)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Ida K Haugen (IK)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Francis Berenbaum (F)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Philip G Conaghan (PG)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Mariko L Ishimori (ML)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Wilma Smeets (W)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Désirée van der Heijde (D)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center.

Margreet Kloppenburg (M)

From the Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Division of Academic Rheumatology, University of Nottingham; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre, Leeds, UK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine Hospital AP-HP, DHU i2B, Paris, France; Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA. g.kloppenburg@lumc.nl.
R. Wittoek, MD, PhD, Department of Rheumatology, Ghent University Hospital, Ghent University; F.P. Kroon, MD, Department of Rheumatology, Leiden University Medical Center; B. Kundakci, PT, MSc, Division of Academic Rheumatology, University of Nottingham; A. Abhishek, MD, MRCP, PhD, Division of Academic Rheumatology, University of Nottingham, and National Institute for Health Research, Nottingham Biomedical Research Centre; I.K. Haugen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; F. Berenbaum, MD, PhD, Department of Rheumatology, Sorbonne Université, INSERM, Saint-Antoine hospital AP-HP, DHU i2B; P.G. Conaghan MBBS, PhD, FRACP, FRCP, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research, Leeds Biomedical Research Centre; M.L. Ishimori, MD, Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center; W. Smeets, Patient Representative, Department of Rheumatology, Leiden University Medical Center; D. van der Heijde, MD, PhD, Department of Rheumatology, Leiden University Medical Center; M. Kloppenburg, MD, PhD, Department of Rheumatology, and Department of Clinical Epidemiology, Leiden University Medical Center. g.kloppenburg@lumc.nl.

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