Association of Smoking and Obesity on the Risk of Developing Primary Sjögren Syndrome: A Population-based Cohort Study.
EPIDEMIOLOGY
OBESITY
SJÖGREN SYNDROME
SMOKING
Journal
The Journal of rheumatology
ISSN: 0315-162X
Titre abrégé: J Rheumatol
Pays: Canada
ID NLM: 7501984
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
accepted:
09
10
2018
pubmed:
17
1
2019
medline:
22
9
2020
entrez:
17
1
2019
Statut:
ppublish
Résumé
To explore the role of smoking and obesity in primary Sjögren syndrome (pSS). Olmsted County (Minnesota, USA) residents (n = 106) diagnosed with pSS from 2000 to 2015 were compared to 3 controls without pSS and matched for age and sex who were randomly selected from Olmsted County residents. Current smokers were less likely to be pSS cases (OR 0.34, 95% CI 0.14-0.85), while there was no association between former smoking and case/control status (OR 1.27, 95% CI 0.80-2.03) compared to never smokers. Smoking status was not associated with antinuclear antibody, anti-SSA, anti-SSB, or rheumatoid factor positivity (p > 0.05). OR for obesity was 0.79 (95% CI 0.48-1.30). In this population-based study, current smoking was inversely associated with case/control status, while body mass index lacked any association.
Identifiants
pubmed: 30647188
pii: jrheum.180481
doi: 10.3899/jrheum.180481
pmc: PMC6606330
mid: NIHMS1509449
doi:
Substances chimiques
Antibodies, Antinuclear
0
SS-A antibodies
0
SS-B antibodies
0
Rheumatoid Factor
9009-79-4
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
727-730Subventions
Organisme : NIA NIH HHS
ID : R01 AG034676
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000135
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002377
Pays : United States
Références
Ann Rheum Dis. 2000 Jan;59(1):54-60
pubmed: 10627428
Am J Med. 2006 Jun;119(6):503.e1-9
pubmed: 16750964
Am J Epidemiol. 2011 May 1;173(9):1059-68
pubmed: 21430193
Mod Rheumatol. 2011 Dec;21(6):602-7
pubmed: 21445716
Rheumatology (Oxford). 2012 Mar;51(3):552-6
pubmed: 22120603
Arthritis Care Res (Hoboken). 2013 Jan;65(1):71-7
pubmed: 22514156
Nutr Diabetes. 2012 Dec 03;2:e54
pubmed: 23208415
J Autoimmun. 2014 Jun;51:51-6
pubmed: 24411404
Rheumatology (Oxford). 2015 Apr;54(4):655-9
pubmed: 25240612
Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):205-17
pubmed: 25732745
Rheumatology (Oxford). 2015 Dec;54(12):2230-8
pubmed: 26231345
RMD Open. 2015 Feb 20;1(1):e000022
pubmed: 26509054
Respir Med. 2016 Nov;120:87-90
pubmed: 27817820
Arthritis Care Res (Hoboken). 2017 Oct;69(10):1612-1616
pubmed: 27998024
PLoS One. 2017 Feb 6;12(2):e0170249
pubmed: 28166540
Arthritis Res Ther. 2017 Mar 7;19(1):50
pubmed: 28270185
Mayo Clin Proc. 2017 May;92(5):734-743
pubmed: 28389066
Ann Rheum Dis. 2018 Feb;77(2):196-202
pubmed: 28988206