Tuberculosis following PD-1 blockade for cancer immunotherapy.


Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
16 01 2019
Historique:
received: 09 03 2018
revised: 02 10 2018
accepted: 06 12 2018
entrez: 18 1 2019
pubmed: 18 1 2019
medline: 23 2 2020
Statut: ppublish

Résumé

Because of the well-established therapeutic benefit of boosting antitumor responses through blockade of the T cell inhibitory receptor PD-1, it has been proposed that PD-1 blockade could also be useful in infectious disease settings, including

Identifiants

pubmed: 30651320
pii: 11/475/eaat2702
doi: 10.1126/scitranslmed.aat2702
pmc: PMC7372940
mid: NIHMS1602940
pii:
doi:

Substances chimiques

Antibodies, Monoclonal, Humanized 0
Programmed Cell Death 1 Receptor 0
Nivolumab 31YO63LBSN
pembrolizumab DPT0O3T46P

Types de publication

Case Reports Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCI NIH HHS
ID : P30 CA015704
Pays : United States
Organisme : NCI NIH HHS
ID : K24 CA139052
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA154967
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA186717
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA154967
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA162522
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI074492
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA014089
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA138292
Pays : United States

Informations de copyright

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Références

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Auteurs

Daniel L Barber (DL)

T Lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA. barberd@niaid.nih.gov sharone@mail.nih.gov.

Shunsuke Sakai (S)

T Lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.

Ragini R Kudchadkar (RR)

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.

Steven P Fling (SP)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Cancer Immunotherapy Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Tracey A Day (TA)

Clinical Immunology Group, Infectious Disease Research Institute, Seattle, WA 98102, USA.

Julie A Vergara (JA)

Clinical Immunology Group, Infectious Disease Research Institute, Seattle, WA 98102, USA.

David Ashkin (D)

Division of Infectious Diseases and Global Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA.

Jonathan H Cheng (JH)

Norris Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

Lisa M Lundgren (LM)

Cancer Immunotherapy Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Vanessa N Raabe (VN)

Division of Infectious Diseases, Emory University, Atlanta, GA 30322, USA.

Colleen S Kraft (CS)

Department of Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA 30322, USA.

Jorge J Nieva (JJ)

Norris Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

Martin A Cheever (MA)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Cancer Immunotherapy Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Paul T Nghiem (PT)

Division of Dermatology, Department of Medicine, University of Washington, Seattle, WA 98195, USA.

Elad Sharon (E)

Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD 20892, USA. barberd@niaid.nih.gov sharone@mail.nih.gov.

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Classifications MeSH