Endoscopic optical coherence tomography angiography using a forward imaging piezo scanner probe.
MEMS technology
angiography
endoscopy
optical coherence tomography
Journal
Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
08
10
2018
revised:
10
01
2019
accepted:
11
01
2019
pubmed:
18
1
2019
medline:
17
6
2020
entrez:
18
1
2019
Statut:
ppublish
Résumé
A forward imaging endoscope for optical coherence tomography angiography (OCTA) featuring a piezoelectric fiber scanner is presented. Imaging is performed with an optical coherence tomography (OCT) system incorporating an akinetic light source with a center wavelength of 1300 nm, bandwidth of 90 nm and A-line rate of 173 kHz. The endoscope operates in contact mode to avoid motion artifacts, in particular, beneficial for OCTA measurements, and achieves a transversal resolution of 12 μm in air at a rigid probe size of 4 mm in diameter and 11.3 mm in length. A spiral scan pattern is generated at a scanning frequency of 360 Hz to sample a maximum field of view of 1.3 mm. OCT images of a human finger as well as visualization of microvasculature of the human palm are presented both in two and three dimensions. The combination of morphological tissue contrast with qualitative dynamic blood flow information within this endoscopic imaging approach potentially enables improved early diagnostic capabilities of internal organs for diseases such as bladder cancer.
Identifiants
pubmed: 30652423
doi: 10.1002/jbio.201800382
pmc: PMC7065608
doi:
Types de publication
Letter
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e201800382Subventions
Organisme : Bundesministerium für Wissenschaft, Forschung und Wirtschaft
Pays : International
Organisme : H2020 European Research Council
ID : 667933
Pays : International
Organisme : H2020 Marie Skłodowska-Curie Actions
ID : 721766
Pays : International
Organisme : German Research Foundation
ID : EXC 1086
Pays : International
Organisme : Horizon 2020
Pays : International
Informations de copyright
© 2019 The Authors. Journal of Biophotonics published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Références
Opt Lett. 1996 Apr 1;21(7):543-5
pubmed: 19865466
Biomed Opt Express. 2016 Jul 12;7(8):3032-48
pubmed: 27570695
Opt Lett. 2017 Aug 15;42(16):3193-3196
pubmed: 28809905
Opt Express. 2006 Aug 21;14(17):7821-40
pubmed: 19529151
Nat Med. 2013 Feb;19(2):238-40
pubmed: 23314056
Opt Express. 2014 Feb 10;22(3):2632-55
pubmed: 24663556
Opt Express. 2018 Feb 19;26(4):4780-4785
pubmed: 29475322
J Biophotonics. 2008 May;1(2):114-28
pubmed: 19343643
Opt Lett. 2004 Aug 1;29(15):1763-5
pubmed: 15352362
Biomed Opt Express. 2017 Apr 07;8(5):2405-2444
pubmed: 28663882
Opt Lett. 2018 Sep 15;43(18):4386-4389
pubmed: 30211870
Prog Retin Eye Res. 2008 Jan;27(1):45-88
pubmed: 18036865
J Biophotonics. 2010 Jun;3(5-6):385-407
pubmed: 20336702
Opt Lett. 1997 Nov 1;22(21):1618-20
pubmed: 18188315
Science. 1991 Nov 22;254(5035):1178-81
pubmed: 1957169
Opt Lett. 2006 Apr 15;31(8):1076-8
pubmed: 16625908
Appl Opt. 2003 Nov 1;42(31):6422-6
pubmed: 14649286
J Biophotonics. 2019 Apr;12(4):e201800382
pubmed: 30652423
Prog Retin Eye Res. 2014 Jul;41:26-43
pubmed: 24704352