Role of Bile in Infectious Disease: the Gall of 7α-Dehydroxylating Gut Bacteria.


Journal

Cell chemical biology
ISSN: 2451-9448
Titre abrégé: Cell Chem Biol
Pays: United States
ID NLM: 101676030

Informations de publication

Date de publication:
17 01 2019
Historique:
entrez: 19 1 2019
pubmed: 19 1 2019
medline: 18 10 2019
Statut: ppublish

Résumé

Local antibiotics and quorum sensors produced by gut bacteria regulate microbiota community structure and guard against pathogens. In this issue of Cell Chemical Biology, Kang et al. (2019) guide us through a reciprocal host-antimicrobial interplay that redefines our understanding of Clostridioides (Clostridium) difficile pathogenesis.

Identifiants

pubmed: 30658109
pii: S2451-9456(18)30474-4
doi: 10.1016/j.chembiol.2018.12.010
pmc: PMC6542261
mid: NIHMS1026873
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Bile Acids and Salts 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-3

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI100914
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI116895
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI124290
Pays : United States

Commentaires et corrections

Type : CommentOn

Informations de copyright

Published by Elsevier Ltd.

Références

Res Microbiol. 2015 May;166(4):375-83
pubmed: 25445566
PLoS One. 2018 May 8;13(5):e0196977
pubmed: 29738579
Arch Biochem Biophys. 1963 Apr;101:7-13
pubmed: 13952333
Sci Transl Med. 2018 Oct 24;10(464):
pubmed: 30355801
Cell Chem Biol. 2019 Jan 17;26(1):27-34.e4
pubmed: 30482679
mSphere. 2016 Jan 06;1(1):
pubmed: 27239562
Antimicrob Agents Chemother. 2001 Aug;45(8):2340-7
pubmed: 11451694
Nature. 2015 Jan 8;517(7533):205-8
pubmed: 25337874
PLoS Pathog. 2012;8(10):e1002995
pubmed: 23133377
Nat Rev Dis Primers. 2016 Apr 07;2:16020
pubmed: 27158839

Auteurs

Tor Savidge (T)

Department of Pathology & Immunology, Baylor College of Medicine, Houston TX, 77030, USA; Texas Children's Microbiome Center, Texas Children's Hospital, Houston TX, 77030, USA. Electronic address: tor.savidge@bcm.edu.

Joseph A Sorg (JA)

Department of Biology, Texas A&M University, College Station TX, 77843, USA.

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Classifications MeSH