Antipsychotic drugs scavenge radiation-induced hydroxyl radicals and intracellular ROS formation, and protect apoptosis in human lymphoma U937 cells.

Antipsychotic Agents / pharmacology Apoptosis Humans Hydroxyl Radical / metabolism Lymphoma / drug therapy Reactive Oxygen Species / metabolism U937 Cells
Apoptosis ROS clozapine olanzapine radiation

Journal

Free radical research
ISSN: 1029-2470
Titre abrégé: Free Radic Res
Pays: England
ID NLM: 9423872

Informations de publication

Date de publication:
Mar 2019
Historique:
pubmed: 23 1 2019
medline: 7 9 2019
entrez: 23 1 2019
Statut: ppublish

Résumé

Antioxidant activity has been reported for some atypical antipsychotic drugs; however, the detailed mechanism is not well known. Here, we investigated the effects of atypical antipsychotic drugs on

Identifiants

DOI: 10.1080/10715762.2019.1572889 PMID: 30668194
pubmed: 30668194
doi: 10.1080/10715762.2019.1572889
doi:

Substances chimiques

Antipsychotic Agents 0
Reactive Oxygen Species 0
Hydroxyl Radical 3352-57-6

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

304-312

Auteurs

Qing-Li Zhao (QL)

a Department of Radiology, Graduate School of Medicine and Pharmaceutical Sciences , University of Toyama , Toyama , Japan.

Hiroko Ito (H)

b Department of Neuropsychiatry, Graduate School of Medicine and Pharmaceutical Sciences , University of Toyama , Toyama , Japan.

Takashi Kondo (T)

a Department of Radiology, Graduate School of Medicine and Pharmaceutical Sciences , University of Toyama , Toyama , Japan.

Takashi Uehara (T)

c Department of Neuropsychiatry , Kanazawa Medical University , Ishikawa , Japan.

Masayuki Ikeda (M)

d Department of Biology, Graduate School of Science and Engineering , University of Toyama , Toyama , Japan.

Hitoshi Abe (H)

d Department of Biology, Graduate School of Science and Engineering , University of Toyama , Toyama , Japan.

Jun-Ichi Saitoh (JI)

a Department of Radiology, Graduate School of Medicine and Pharmaceutical Sciences , University of Toyama , Toyama , Japan.

Kyo Noguchi (K)

a Department of Radiology, Graduate School of Medicine and Pharmaceutical Sciences , University of Toyama , Toyama , Japan.

Michio Suzuki (M)

b Department of Neuropsychiatry, Graduate School of Medicine and Pharmaceutical Sciences , University of Toyama , Toyama , Japan.

Masayoshi Kurachi (M)

b Department of Neuropsychiatry, Graduate School of Medicine and Pharmaceutical Sciences , University of Toyama , Toyama , Japan.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Psychoanaleptiques › Tranquillisants › Neuroleptiques › Antipsychotic drugs scavenge radiation-induced...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Antipsychotic drugs scavenge radiation-induced...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Antipsychotic drugs scavenge radiation-induced...
questionsmedicales.fr › Produits chimiques inorganiques › Radical hydroxyle › Antipsychotic drugs scavenge radiation-induced...
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Lymphomes › Antipsychotic drugs scavenge radiation-induced...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Espèces réactives de l'oxygène › Antipsychotic drugs scavenge radiation-induced...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Cellules U937 › Antipsychotic drugs scavenge radiation-induced...