Phenotypic and Genotypic Characterization of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in Asymptomatic Bacteriuria in Pregnancy.
Adolescent
Adult
Anti-Bacterial Agents
/ pharmacology
Asymptomatic Diseases
Bacteriuria
/ epidemiology
Drug Resistance, Multiple, Bacterial
/ genetics
Egypt
/ epidemiology
Enterobacter
/ classification
Enterobacteriaceae Infections
/ epidemiology
Escherichia coli
/ classification
Escherichia coli Infections
/ epidemiology
Female
Gene Expression
Genotype
Humans
Klebsiella Infections
/ epidemiology
Klebsiella pneumoniae
/ classification
Phenotype
Pregnancy
Prevalence
beta-Lactamases
None
CTX-M
asymptomatic bacteriuria
extended spectrum β-lactamases
pregnancy
Journal
Microbial drug resistance (Larchmont, N.Y.)
ISSN: 1931-8448
Titre abrégé: Microb Drug Resist
Pays: United States
ID NLM: 9508567
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
pubmed:
25
1
2019
medline:
30
11
2019
entrez:
25
1
2019
Statut:
ppublish
Résumé
Asymptomatic bacteriuria (ASB) has been consistently observed in pregnancy. However, there is a paucity of data on the prevalence and characteristics of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in ASB in pregnant women. Therefore, we sought to investigate ESBL-producing and multidrug-resistant Enterobacteriaceae in antenatal women with ASB. Urine samples were collected from 310 asymptomatic pregnant women attending primary antenatal clinics and screened for significant bacteriuria. Isolates of Enterobacteriaceae were phenotypically tested for their ESBL production. ESBL genes (CTX-M, TEM, and SHV genes) were then amplified by polymerase chain reaction (PCR). Multiplex PCRs were used to perform phylogenetic typing of ESBL-producing
Identifiants
pubmed: 30676863
doi: 10.1089/mdr.2018.0088
doi:
Substances chimiques
Anti-Bacterial Agents
0
beta-Lactamases
EC 3.5.2.6
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM