Germline and Somatic Tumor Testing in Gynecologic Cancer Care.
Genomics
Germline
Gynecologic cancer
Somatic
Tumor testing
Journal
Obstetrics and gynecology clinics of North America
ISSN: 1558-0474
Titre abrégé: Obstet Gynecol Clin North Am
Pays: United States
ID NLM: 8709551
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
entrez:
27
1
2019
pubmed:
27
1
2019
medline:
21
3
2019
Statut:
ppublish
Résumé
New technologies have advanced the science of tumor biology and genomics. Commercially available germline and somatic testing modalities have the downstream benefits of enabling prevention strategies in women with hereditary cancers and their family members in addition to identifying women who benefit most from novel targeted therapeutics. The matrix of available testing is complex and evolving. Women's health providers need to be versed in benefits and limitations of available testing. Genetic counselors play a pivotal role in interpretation of relevant mutations, and in avoiding common pitfalls, but their skill set is not sufficient to optimally integrate cancer genomics into clinical practice.
Identifiants
pubmed: 30683265
pii: S0889-8545(18)30091-3
doi: 10.1016/j.ogc.2018.09.003
pmc: PMC7480763
mid: NIHMS1602184
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
37-53Subventions
Organisme : NCI NIH HHS
ID : T32 CA060396
Pays : United States
Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.
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