Fasciculating toxicity.
Atropine
Fasciculations
Muscarinic
Nicotinic
Organophosphorus (OP)
Journal
The American journal of emergency medicine
ISSN: 1532-8171
Titre abrégé: Am J Emerg Med
Pays: United States
ID NLM: 8309942
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
29
10
2018
revised:
15
01
2019
accepted:
21
01
2019
pubmed:
29
1
2019
medline:
18
12
2019
entrez:
29
1
2019
Statut:
ppublish
Résumé
Organophosphorus (OP) compound poisoning with suicidal intent is common. It is one of the frequent cause for admission to hospital Emergencies and intensive care units in our region. We describe here a case of 19-year old girl who presented to the Emergency Department with atypical features of OP poisoning. She had perioral, tongue and lower limb fasciculations along with generalized muscle weakness with no or minimal muscarinic effects. OP poisoning with isolated nicotinic receptor mediated effect is often reported in children but in adult it is extremely rare. Based on history and clinical suspicion of nicotinic receptor mediated effect of OP, she was given intravenous atropine along with other supportive treatment. Patient got completely recovered from fasciculations and her motor weakness improved after 6 h of atropine therapy. Emergency physician should keep a high index of suspicion of isolated nicotinic and ganglionic mediated effect of OP and a trial of atropine should be given to the patient.
Identifiants
pubmed: 30686539
pii: S0735-6757(19)30039-7
doi: 10.1016/j.ajem.2019.01.033
pii:
doi:
Substances chimiques
Insecticides
0
Muscarinic Antagonists
0
Atropine
7C0697DR9I
Types de publication
Case Reports
Journal Article
Video-Audio Media
Langues
eng
Sous-ensembles de citation
IM
Pagination
798.e1-798.e2Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.