Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000.
deep-fried food
fruit
head and neck cancers
survival
vegetables
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
25
03
2018
revised:
20
12
2018
accepted:
04
01
2019
pubmed:
31
1
2019
medline:
8
10
2020
entrez:
31
1
2019
Statut:
ppublish
Résumé
The association between diet and head and neck cancer (HNC) survival is unclear. Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status. Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13). Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.
Sections du résumé
BACKGROUND
The association between diet and head and neck cancer (HNC) survival is unclear.
METHODS
Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.
RESULTS
Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).
CONCLUSIONS
Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.
Identifiants
pubmed: 30698303
doi: 10.1002/hed.25660
pmc: PMC7116031
mid: EMS88728
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2074-2084Subventions
Organisme : Department of Health
ID : RP-PG-0707-10034
Pays : United Kingdom
Organisme : Programme Grants for Applied Research
ID : RP-PG-0707-10034
Pays : International
Organisme : Cancer Research UK
ID : C18281
Pays : United Kingdom
Organisme : Cancer Research UK
ID : A19169
Pays : United Kingdom
Informations de copyright
© 2019 Wiley Periodicals, Inc.
Références
Crit Rev Oncol Hematol. 2015 Nov;96(2):328-38
pubmed: 26117315
Int J Oral Maxillofac Surg. 2009 Jan;38(1):31-9
pubmed: 18951763
J Clin Oncol. 2013 Jul 20;31(21):2708-15
pubmed: 23775966
Int J Cancer. 2018 Sep 1;143(5):1105-1113
pubmed: 29604042
Oxid Med Cell Longev. 2012;2012:902716
pubmed: 22690273
Eur J Cancer Prev. 2001 Apr;10(2):191-5
pubmed: 11330465
Oral Oncol. 2004 Oct;40(9):925-31
pubmed: 15380171
PLoS One. 2012;7(6):e38607
pubmed: 22719905
J Clin Oncol. 2009 Apr 20;27(12):1969-75
pubmed: 19289626
Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):1062-9
pubmed: 19036528
J Adolesc Health. 2004 Mar;34(3):163-5
pubmed: 14967337
J Am Diet Assoc. 2003 Oct;103(10):1306-13
pubmed: 14520248
Nutr Cancer. 2010;62(3):322-8
pubmed: 20358469
J Natl Cancer Inst. 2017 Aug 1;109(8):
pubmed: 28376197
Clin Chem. 2005 Oct;51(10):1845-53
pubmed: 16099939
Int J Cancer. 2005 Dec 20;117(6):992-5
pubmed: 15986425
Biochem Pharmacol. 2006 May 14;71(10):1397-421
pubmed: 16563357
J Natl Cancer Inst. 2008 Mar 19;100(6):407-20
pubmed: 18334711
Occup Environ Med. 1998 Oct;55(10):651-6
pubmed: 9930084
Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3368-74
pubmed: 19959684
Br J Cancer. 1999 May;80(3-4):614-20
pubmed: 10408875
N Engl J Med. 2010 Jul 1;363(1):24-35
pubmed: 20530316
Lancet. 2008 May 17;371(9625):1695-709
pubmed: 18486742
Head Neck. 2016 Apr;38 Suppl 1:E1591-7
pubmed: 26614223
Br J Cancer. 2005 Jun 6;92(11):2065-9
pubmed: 15856044
CA Cancer J Clin. 2005 Mar-Apr;55(2):74-108
pubmed: 15761078
Ann Oncol. 2007 Mar;18(3):581-92
pubmed: 17287242
J Clin Diagn Res. 2014 Apr;8(4):ZC01-3
pubmed: 24959505
Oral Oncol. 2010 Jun;46(6):402-6
pubmed: 20350835
Am J Public Health. 1990 Nov;80(11):1323-9
pubmed: 2240298
Metabolism. 1995 Feb;44(2 Suppl 2):18-22
pubmed: 7869932
Mutat Res. 1986 Aug-Sep;171(2-3):115-21
pubmed: 3528833
Clin Otolaryngol. 2016 Dec;41(6):804-809
pubmed: 26436654
Br J Cancer. 2002 Nov 18;87(11):1230-3
pubmed: 12439711
Int J Cancer. 2008 May 15;122(10):2330-6
pubmed: 18092323
BMC Public Health. 2007 Jul 03;7:138
pubmed: 17608935
Cancer Causes Control. 2006 Sep;17(7):957-69
pubmed: 16841263
Laryngoscope. 2018 Nov;128(11):E371-E376
pubmed: 29756240
Am J Clin Nutr. 2013 Feb;97(2):360-8
pubmed: 23269814
Int J Cancer. 2015 Mar 1;136(5):E396-409
pubmed: 25220255
Head Neck. 2017 Jun;39(6):1226-1233
pubmed: 28323362
BMC Cancer. 2014 Dec 17;14:973
pubmed: 25519023
Int J Cancer. 1996 Jan 26;65(3):308-13
pubmed: 8575849