Successful outcome of the transitional process of inflammatory bowel disease from pediatric to adult age: A five years experience.


Journal

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
ISSN: 1878-3562
Titre abrégé: Dig Liver Dis
Pays: Netherlands
ID NLM: 100958385

Informations de publication

Date de publication:
04 2019
Historique:
received: 03 09 2018
revised: 23 11 2018
accepted: 27 11 2018
pubmed: 2 2 2019
medline: 19 9 2019
entrez: 2 2 2019
Statut: ppublish

Résumé

The transitional process of young patients affected by inflammatory bowel disease from pediatric to adult care is a crucial step. Our study aimed to investigate the 1-year success outcome of this transitional process. From 2013 to 2018, we evaluated the transitional process of patients with Crohn's disease or ulcerative colitis. For each patient, the following parameters 12 months before and 12 months after the transition were evaluated: Body Mass Index, disease activity and smoker status, number of outpatient visits and the pharmacological therapy, the number of disease exacerbations, hospitalizations and surgical interventions. We enrolled 106 patients with IBD. No statistically significant difference was found between patients' Body Mass Index before and after transition. There was a significant reduction in the number of exacerbations and hospitalizations in the 12 months post-transition (pre-transition exacerbations: 0.74 ± 0.79, post-transition exacerbations: 0.35 ± 0.57, p < 0.001; pre-transition hospitalizations: 0.28 ± 0.44, post-transition hospitalizations: 0.1 ± 0.3, p < 0.001). In contrast, there was no significant difference in the number of outpatient visits (3.40 ± 1.4 vs 3.25 ± 1.2; p = ns) and of patients undergoing surgery (0.9% vs 1.8%, p = ns). The parameters used as success indicators of the transition program confirm the achievement of continuity of care from Pediatrics to adult Gastroenterology, in a critical phase of the natural history of IBD patients.

Identifiants

pubmed: 30704905
pii: S1590-8658(18)31273-8
doi: 10.1016/j.dld.2018.11.034
pii:
doi:

Types de publication

Comparative Study Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

524-528

Informations de copyright

Copyright © 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Auteurs

Anna Testa (A)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy. Electronic address: annatesta82@virgilio.it.

Eleonora Giannetti (E)

Department of Translational Medical Science, Section of Pediatrics, University of Naples 'Federico II', Naples, Italy.

Antonio Rispo (A)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

Matilde Rea (M)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

Erasmo Miele (E)

Department of Translational Medical Science, Section of Pediatrics, University of Naples 'Federico II', Naples, Italy.

Elena Scarpato (E)

Department of Translational Medical Science, Section of Pediatrics, University of Naples 'Federico II', Naples, Italy.

Anna Opramolla (A)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

Olga Maria Nardone (OM)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

Nicola Imperatore (N)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

Imma Di Luna (I)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

Annamaria Staiano (A)

Department of Translational Medical Science, Section of Pediatrics, University of Naples 'Federico II', Naples, Italy.

Fabiana Castiglione (F)

Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

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