Immunologic Effects of the Microbiota in Organ Transplantation.

Gastrointestinal Microbiome / immunology Graft Rejection / microbiology Humans Immunologic Factors / adverse effects Immunosuppression Therapy Organ Transplantation
Immune regulation Microbiota Transplantation

Journal

Clinics in laboratory medicine
ISSN: 1557-9832
Titre abrégé: Clin Lab Med
Pays: United States
ID NLM: 8100174

Informations de publication

Date de publication:
03 2019
Historique:
entrez: 3 2 2019
pubmed: 3 2 2019
medline: 10 9 2019
Statut: ppublish

Résumé

The microbiota is a community of microbes that colonizes body surfaces. It has many effects that influence immune activation and regulation. The success of organ transplantation is limited by rejection of grafts by the immune system so it is important to understand how immunologic responses are controlled in this setting. This review discusses the immunologic effects of the microbiota and how this microbial community may affect organ transplant rejection.

Identifiants

DOI: 10.1016/j.cll.2018.10.010 PMID: 30709506
pubmed: 30709506
pii: S0272-2712(18)31206-X
doi: 10.1016/j.cll.2018.10.010
pii:
doi:

Substances chimiques

Immunologic Factors 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

185-195

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Kevin Rey (K)

Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada; Centre for Cell Biology, Development and Disease, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada.

Jonathan C Choy (JC)

Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada; Centre for Cell Biology, Development and Disease, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada. Electronic address: jonathan.choy@sfu.ca.

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Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Immunologic Effects of the Microbiota in Organ...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunologie en transplantation › Réaction de l'hôte contre le greffon › Rejet du greffon › Immunologic Effects of the Microbiota in Organ...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Immunologic Effects of the Microbiota in Organ...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Immunologic Effects of the Microbiota in Organ...
questionsmedicales.fr › Techniques d'investigation › Techniques immunologiques › Immunosuppression thérapeutique › Immunologic Effects of the Microbiota in Organ...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation d'organe › Immunologic Effects of the Microbiota in Organ...