Lipid-Conjugated Rigidochromic Probe Discloses Membrane Alteration in Model Cells of Krabbe Disease.


Journal

Biophysical journal
ISSN: 1542-0086
Titre abrégé: Biophys J
Pays: United States
ID NLM: 0370626

Informations de publication

Date de publication:
05 02 2019
Historique:
received: 25 05 2018
revised: 15 10 2018
accepted: 16 11 2018
pubmed: 3 2 2019
medline: 21 1 2020
entrez: 3 2 2019
Statut: ppublish

Résumé

The plasma membrane of cells has a complex architecture based on the bidimensional liquid-crystalline bilayer arrangement of phospho- and sphingolipids, which in turn embeds several proteins and is connected to the cytoskeleton. Several studies highlight the spatial membrane organization into more ordered (L

Identifiants

pubmed: 30709620
pii: S0006-3495(18)34509-0
doi: 10.1016/j.bpj.2018.11.3141
pmc: PMC6369402
pii:
doi:

Substances chimiques

Lipid Bilayers 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

477-486

Informations de copyright

Copyright © 2019 Biophysical Society. Published by Elsevier Inc. All rights reserved.

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Auteurs

Gerardo Abbandonato (G)

NEST, Scuola Normale Superiore and Istituto Nanoscienze CNR (NANO-CNR), Piazza San Silvestro, Pisa, Italy.

Barbara Storti (B)

NEST, Scuola Normale Superiore and Istituto Nanoscienze CNR (NANO-CNR), Piazza San Silvestro, Pisa, Italy.

Ilaria Tonazzini (I)

NEST, Scuola Normale Superiore and Istituto Nanoscienze CNR (NANO-CNR), Piazza San Silvestro, Pisa, Italy.

Martin Stöckl (M)

Bioimaging Center, Department of Biology, Universität Konstanz, Konstanz, Germany.

Vinod Subramaniam (V)

Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Nanobiophysics, MESA+ Institute for Nanotechnology and MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands.

Costanza Montis (C)

Department of Chemistry and CSGI, University of Florence, Florence, Italy.

Riccardo Nifosì (R)

NEST, Scuola Normale Superiore and Istituto Nanoscienze CNR (NANO-CNR), Piazza San Silvestro, Pisa, Italy.

Marco Cecchini (M)

NEST, Scuola Normale Superiore and Istituto Nanoscienze CNR (NANO-CNR), Piazza San Silvestro, Pisa, Italy.

Giovanni Signore (G)

NEST, Scuola Normale Superiore and Istituto Nanoscienze CNR (NANO-CNR), Piazza San Silvestro, Pisa, Italy; Center for Nanotechnology Innovation@NEST, Istituto Italiano di Tecnologia, Pisa, Italy. Electronic address: giovanni.signore@sns.it.

Ranieri Bizzarri (R)

NEST, Scuola Normale Superiore and Istituto Nanoscienze CNR (NANO-CNR), Piazza San Silvestro, Pisa, Italy; Department of Chemistry and CSGI, University of Florence, Florence, Italy. Electronic address: r.bizzarri@sns.it.

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Classifications MeSH