Topographic organization of connections between prefrontal cortex and mediodorsal thalamus: Evidence for a general principle of indirect thalamic pathways between directly connected cortical areas.
Diffusion MRI
Macaque
Mediodorsal thalamus
Prefrontal cortex
Replication principle
Thalamocortical
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
01 04 2019
01 04 2019
Historique:
received:
14
09
2018
revised:
13
01
2019
accepted:
30
01
2019
pubmed:
4
2
2019
medline:
25
1
2020
entrez:
4
2
2019
Statut:
ppublish
Résumé
Our ability to act flexibly, according to goals and context, is known as cognitive control. Hierarchical levels of control, reflecting different levels of abstraction, are represented across prefrontal cortex (PFC). Although the mediodorsal thalamic nucleus (MD) is extensively interconnected with PFC, the role of MD in cognitive control is unclear. Tract tracer studies in macaques, involving subsets of PFC areas, have converged on coarse MD-PFC connectivity principles; but proposed finer-grained topographic schemes, which constrain interactions between MD and PFC, disagree in many respects. To investigate a unifying topographic scheme, we performed probabilistic tractography on diffusion MRI data from eight macaque monkeys, and estimated the probable paths connecting MD with each of all 19 architectonic areas of PFC. We found a connectional topography where the orderly progression from ventromedial to anterior to posterolateral PFC was represented from anteromedial to posterolateral MD. The projection zones of posterolateral PFC areas in MD showed substantial overlap, and those of ventral and anteromedial PFC areas in MD overlapped. The exception was cingulate area 24: its projection zone overlapped with projections zones of all other PFC areas. Overall, our data suggest that nearby, functionally related, directly connected PFC areas have partially overlapping projection zones in MD, consistent with a role for MD in coordinating communication across PFC. Indeed, the organizing principle for PFC projection zones in MD appears to reflect the flow of information across the hierarchical, multi-level PFC architecture. In addition, cingulate area 24 may have privileged access to influence thalamocortical interactions involving all other PFC areas.
Identifiants
pubmed: 30711468
pii: S1053-8119(19)30084-9
doi: 10.1016/j.neuroimage.2019.01.078
pmc: PMC6506175
mid: NIHMS1527334
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
832-846Subventions
Organisme : NIH HHS
ID : P51 OD011106
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH110311
Pays : United States
Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.
Références
Brain Res Bull. 2009 Feb 16;78(2-3):69-74
pubmed: 18950692
Nat Neurosci. 2003 Jul;6(7):750-7
pubmed: 12808459
J Neurosci. 2013 Feb 13;33(7):3190-201
pubmed: 23407972
Brain. 1993 Apr;116 ( Pt 2):369-82
pubmed: 8461971
Neuropsychopharmacology. 2010 Jan;35(1):4-26
pubmed: 19812543
Cortex. 2012 Jan;48(1):46-57
pubmed: 21872854
Cereb Cortex. 2016 Feb;26(2):467-76
pubmed: 25217467
Neuroscience. 2009 Jul 21;161(4):1067-81
pubmed: 19376204
Exp Neurol. 1968 May;21(1):20-34
pubmed: 4970775
J Comp Neurol. 1999 Jun 21;409(1):131-52
pubmed: 10363716
J Comp Neurol. 2017 Jan 1;525(1):166-185
pubmed: 27275581
Neuropsychologia. 2003;41(10):1330-44
pubmed: 12757906
J Neurosci. 2016 Jun 22;36(25):6758-70
pubmed: 27335406
Nature. 2017 May 11;545(7653):219-223
pubmed: 28467827
Nat Neurosci. 2013 Aug;16(8):1140-5
pubmed: 23792944
Neuron. 2013 Jul 24;79(2):217-40
pubmed: 23889930
J Cogn Neurosci. 2007 Dec;19(12):2082-99
pubmed: 17892391
J Neurosci. 2006 Aug 9;26(32):8368-76
pubmed: 16899732
J Comp Neurol. 1981 Aug 10;200(3):407-31
pubmed: 7276245
Nat Neurosci. 2016 Sep 27;19(10):1280-5
pubmed: 27669988
Science. 1979 Apr 13;204(4389):205-7
pubmed: 107587
Science. 2012 Aug 10;337(6095):753-6
pubmed: 22879517
Neuron. 2010 Apr 29;66(2):315-26
pubmed: 20435006
Cortex. 2012 Jan;48(1):58-81
pubmed: 21481342
J Comp Neurol. 1988 Mar 1;269(1):130-46
pubmed: 3361000
Annu Rev Psychol. 2013;64:135-68
pubmed: 23020641
Magn Reson Med. 1995 Jul;34(1):65-73
pubmed: 7674900
Exp Brain Res. 1994;99(3):383-98
pubmed: 7957718
Neurocase. 2014 Apr;20(2):121-32
pubmed: 23030052
J Comp Neurol. 1988 Nov 8;277(2):195-213
pubmed: 2466057
Brain Res. 1976 Jun 25;110(1):21-38
pubmed: 819108
J Comp Neurol. 1989 Aug 15;286(3):353-75
pubmed: 2768563
Nat Neurosci. 2016 Sep 27;19(10):1286-91
pubmed: 27669989
J Comp Neurol. 1993 Nov 1;337(1):1-31
pubmed: 7506270
J Comp Neurol. 2004 May 17;473(1):107-27
pubmed: 15067722
J Comp Neurol. 1991 Oct 22;312(4):509-24
pubmed: 1761739
Prog Neurobiol. 2004 Apr;72(5):341-72
pubmed: 15157726
Brain Res. 1975 Feb 7;84(2):169-80
pubmed: 803392
J Neurosci. 2008 Jul 9;28(28):7143-52
pubmed: 18614684
Neuroimage. 2016 Jan 1;124(Pt A):238-247
pubmed: 26343320
J Anat. 1938 Oct;73(Pt 1):37-93
pubmed: 17104750
Med Image Anal. 2001 Jun;5(2):143-56
pubmed: 11516708
Neurosci Biobehav Rev. 2013 Sep;37(8):1434-44
pubmed: 23727051
Neuron. 2011 Jul 28;71(2):209-23
pubmed: 21791281
Neuron. 2016 Jan 6;89(1):209-20
pubmed: 26748092
Behav Neurosci. 2003 Dec;117(6):1161-8
pubmed: 14674837
Brain Res. 1978 Dec 29;159(2):279-96
pubmed: 103596
J Neurosci. 2005 Sep 28;25(39):8854-66
pubmed: 16192375
J Chem Neuroanat. 2003 Dec;26(4):317-30
pubmed: 14729134
Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E1020-7
pubmed: 25691741
Neurosci Biobehav Rev. 2015 Jul;54:76-88
pubmed: 25757689
Nat Commun. 2013;4:2409
pubmed: 24008252
Eur J Neurosci. 2002 Jul;16(2):291-310
pubmed: 12169111
Magn Reson Med. 2003 Nov;50(5):1077-88
pubmed: 14587019
Exp Brain Res. 2008 Mar;186(1):131-41
pubmed: 18038127
Neuroimage. 2007 Jan 1;34(1):144-55
pubmed: 17070705
J Comp Neurol. 1991 Nov 1;313(1):65-94
pubmed: 1761756
J Comp Neurol. 1983 Oct 10;220(1):116-25
pubmed: 6315780
Acta Neurobiol Exp (Wars). 1980;40(1):7-25
pubmed: 7424595
Trends Neurosci. 2008 Dec;31(12):599-608
pubmed: 18835649
Magn Reson Med. 2005 Sep;54(3):586-93
pubmed: 16086311
Eur J Neurosci. 2007 Oct;26(7):2005-24
pubmed: 17892479
Philos Trans R Soc Lond B Biol Sci. 2003 Oct 29;358(1438):1605-24
pubmed: 14561322
Nat Neurosci. 2009 Apr;12(4):515-22
pubmed: 19252496
Science. 1971 Aug 13;173(3997):652-4
pubmed: 4998337
Neuroimage. 2004;23 Suppl 1:S208-19
pubmed: 15501092
J Neurosci. 2000 Mar 15;20(6):2369-82
pubmed: 10704511
J Neurophysiol. 1989 Feb;61(2):331-49
pubmed: 2918358
Ann N Y Acad Sci. 2007 Dec;1121:10-32
pubmed: 17698996
J Comp Neurol. 1985 Dec 22;242(4):535-60
pubmed: 2418080
Brain Res. 1975 Jan 10;83(2):191-212
pubmed: 1109293
J Comp Neurol. 1977 May 1;173(1):147-64
pubmed: 403205
Biol Psychiatry. 2018 Apr 15;83(8):648-656
pubmed: 29275841
J Comp Neurol. 1987 Feb 8;256(2):175-210
pubmed: 3549796
Exp Brain Res. 1997 Jul;115(3):430-44
pubmed: 9262198
Annu Rev Neurosci. 2001;24:167-202
pubmed: 11283309
Brain Res. 1973 Oct 26;61:79-91
pubmed: 4204130
J Comp Neurol. 1953 Jun;98(3):433-48
pubmed: 13069630
Science. 2003 Nov 14;302(5648):1181-5
pubmed: 14615530
Science. 1997 May 2;276(5313):821-4
pubmed: 9115211
J Cogn Neurosci. 2006 Jun;18(6):932-48
pubmed: 16839301
J Neurosci. 2002 Sep 15;22(18):8117-32
pubmed: 12223566
Neuropsychologia. 2011 Apr;49(5):777-789
pubmed: 21255590
Trends Cogn Sci. 2008 May;12(5):201-8
pubmed: 18420448
Neuroimage. 2009 Mar;45(1 Suppl):S173-86
pubmed: 19059349
Psychol Rev. 2001 Jul;108(3):624-52
pubmed: 11488380
Neuroimage. 2016 Jan 15;125:1063-1078
pubmed: 26481672
Exp Brain Res. 1977 Sep 28;29(3-4):299-322
pubmed: 410652
Neuroimage. 2010 Jun;51(2):555-64
pubmed: 20206702
Brain Res. 1973 Oct 26;61:93-105
pubmed: 4204131
Nat Neurosci. 2012 Jun;15(6):905-12
pubmed: 22561455
Front Behav Neurosci. 2013 Dec 10;7:198
pubmed: 24339805
Annu Rev Neurosci. 2010;33:173-202
pubmed: 20331363
Nat Rev Neurosci. 2009 Sep;10(9):659-69
pubmed: 19672274
Exp Brain Res. 1994;102(2):259-71
pubmed: 7705504
Front Syst Neurosci. 2014 May 09;8:83
pubmed: 24847225