Chitosan Gels and Cryogels Cross-Linked with Diglycidyl Ethers of Ethylene Glycol and Polyethylene Glycol in Acidic Media.
Animals
Cross-Linking Reagents
/ chemistry
Cryogels
/ chemical synthesis
Drugs, Chinese Herbal
/ chemical synthesis
Elastic Modulus
Ethylene Glycol
/ chemistry
Hydrogen-Ion Concentration
Male
Materials Testing
Mice
Mice, Inbred CBA
Nuclear Magnetic Resonance, Biomolecular
Polyethylene Glycols
/ chemistry
Porosity
Spectroscopy, Fourier Transform Infrared
Journal
Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849
Informations de publication
Date de publication:
08 04 2019
08 04 2019
Historique:
pubmed:
7
2
2019
medline:
28
4
2020
entrez:
7
2
2019
Statut:
ppublish
Résumé
Here we show that the efficacy of the chitosan interaction with diglycidyl ethers of glycols significantly depends on pH and the nature of acid used to dissolve chitosan. In solutions of hydrochloric acid, cross-linking with diglycidyl ethers of ethylene glycol (EGDGE) and polyethylene glycol (PEGDGE) at room and subzero temperatures yields mechanically stable chitosan gels and cryogels, while in acetic acid solutions only weak chitosan gels can be formed under the same conditions. A combination of elemental analysis, FT-IR spectroscopy, and solid state
Identifiants
pubmed: 30726063
doi: 10.1021/acs.biomac.8b01817
doi:
Substances chimiques
Cross-Linking Reagents
0
Cryogels
0
Drugs, Chinese Herbal
0
choto-san
0
Polyethylene Glycols
3WJQ0SDW1A
Ethylene Glycol
FC72KVT52F
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM