Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII.


Journal

Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203

Informations de publication

Date de publication:
Dec 2019
Historique:
entrez: 9 2 2019
pubmed: 9 2 2019
medline: 15 3 2019
Statut: ppublish

Résumé

Two acetazolamide (AAZ) complexes with ruthenium(II) η

Identifiants

pubmed: 30734595
doi: 10.1080/14756366.2018.1547288
pmc: PMC6327979
doi:

Substances chimiques

Antigens, Neoplasm 0
Carbonic Anhydrase Inhibitors 0
Organometallic Compounds 0
Ruthenium 7UI0TKC3U5
Carbonic Anhydrase I EC 4.2.1.-
Carbonic Anhydrase II EC 4.2.1.-
CA9 protein, human EC 4.2.1.1
Carbonic Anhydrase IX EC 4.2.1.1
Carbonic Anhydrases EC 4.2.1.1
carbonic anhydrase XII EC 4.2.1.1
Acetazolamide O3FX965V0I

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

388-393

Références

Dalton Trans. 2018 Jul 17;47(28):9367-9384
pubmed: 29951658
J Biol Chem. 1971 Apr 25;246(8):2561-73
pubmed: 4994926

Auteurs

Sara Seršen (S)

a Faculty of Chemistry and Chemical Technology , University of Ljubljana , Ljubljana , Slovenia.

Katja Traven (K)

a Faculty of Chemistry and Chemical Technology , University of Ljubljana , Ljubljana , Slovenia.

Jakob Kljun (J)

a Faculty of Chemistry and Chemical Technology , University of Ljubljana , Ljubljana , Slovenia.

Iztok Turel (I)

a Faculty of Chemistry and Chemical Technology , University of Ljubljana , Ljubljana , Slovenia.

Claudiu T Supuran (CT)

b Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche , Università degli Studi di Firenze , Florence , Italy.

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Classifications MeSH