Controlled light-induced gas phase nitric oxide release from S-nitrosothiol-doped silicone rubber films.

Drug Carriers / chemistry Drug Liberation Gases / chemistry Kinetics Membranes, Artificial Nitric Oxide / chemistry Nitric Oxide Donors / chemistry S-Nitroso-N-Acetylpenicillamine / chemistry S-Nitrosoglutathione / chemistry Silicones / chemistry Ultraviolet Rays
GSNO Gas phase Inhalation NO Nitric oxide Photo release S-nitrosothiol SNAP

Journal

Nitric oxide : biology and chemistry
ISSN: 1089-8611
Titre abrégé: Nitric Oxide
Pays: United States
ID NLM: 9709307

Informations de publication

Date de publication:
01 05 2019
Historique:
received: 02 10 2018
revised: 12 11 2018
accepted: 31 01 2019
pubmed: 9 2 2019
medline: 28 8 2019
entrez: 9 2 2019
Statut: ppublish

Résumé

The light induced nitric oxide (NO) release properties of S-nitroso-N-acetylpenicillamine (SNAP) and S-nitrosoglutathione (GSNO) NO donors doped within polydimethylsiloxane (PDMS) films (PDMS-SNAP and PDMS-GSNO respectively) for potential inhaled NO (iNO) applications is examined. To achieve photolytic release of gas phase NO from the PDMS-SNAP and PDMS-GSNO films, narrow-band LED light sources are employed and the NO concentration in a N

Identifiants

DOI: 10.1016/j.niox.2019.01.016 PMID: 30735785 PMC: PMC8740643
pubmed: 30735785
pii: S1089-8603(18)30274-X
doi: 10.1016/j.niox.2019.01.016
pmc: PMC8740643
mid: NIHMS1763606
pii:
doi:

Substances chimiques

Drug Carriers 0
Gases 0
Membranes, Artificial 0
Nitric Oxide Donors 0
Silicones 0
Nitric Oxide 31C4KY9ESH
S-Nitrosoglutathione 57564-91-7
S-Nitroso-N-Acetylpenicillamine 79032-48-7

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

31-37

Subventions

Organisme : NHLBI NIH HHS
ID : F32 HL127981
Pays : United States
Organisme : NIBIB NIH HHS
ID : R21 EB024038
Pays : United States

Informations de copyright

Copyright © 2019. Published by Elsevier Inc.

Références

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Auteurs

Gergely Lautner (G)

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, 48109, USA; Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.

Blake Stringer (B)

Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.

Elizabeth J Brisbois (EJ)

Department of Materials Science and Engineering, University of Central Florida, Orlando, FL, 32816, USA.

Mark E Meyerhoff (ME)

Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: mmeyerho@umich.edu.

Steven P Schwendeman (SP)

Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: schwende@umich.edu.

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Classifications MeSH

questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Vecteurs de médicaments › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Libération de médicament › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Donneur d'oxyde nitrique › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés soufrés › Pénicillamine › N-Acétyl-S-nitroso-pénicillamine › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › Glutathion › S-Nitroso-glutathion › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Siloxanes › Silicone › Controlled light-induced gas phase nitric...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Lumière du soleil › Rayons ultraviolets › Controlled light-induced gas phase nitric...