Adjuvant and antigenic properties of Mycobacterium avium subsp. paratuberculosis on experimental autoimmune encephalomyelitis.

Adjuvants, Immunologic / administration & dosage Animals Encephalomyelitis, Autoimmune, Experimental / immunology Female Mice Mice, Inbred C57BL Mycobacterium avium subsp. paratuberculosis / immunology
Adjuvant C57BL/6J mice Experimental autoimmune encephalomyelitis Mycobacterium avium subsp. paratuberculosis

Journal

Journal of neuroimmunology
ISSN: 1872-8421
Titre abrégé: J Neuroimmunol
Pays: Netherlands
ID NLM: 8109498

Informations de publication

Date de publication:
15 05 2019
Historique:
received: 04 12 2018
revised: 07 01 2019
accepted: 22 01 2019
pubmed: 11 2 2019
medline: 4 12 2019
entrez: 11 2 2019
Statut: ppublish

Résumé

Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne's disease in ruminants, has been linked as a possible risk factor for human multiple sclerosis. In the current study we investigated the adjuvant effect of MAP on experimental autoimmune encephalomyelitis (EAE). Groups of C57BL/6 mice were actively immunized with myelin oligodendrocyte glycoprotein (MOG)

Identifiants

DOI: 10.1016/j.jneuroim.2019.01.013 PMID: 30738572
pubmed: 30738572
pii: S0165-5728(18)30552-6
doi: 10.1016/j.jneuroim.2019.01.013
pii:
doi:

Substances chimiques

Adjuvants, Immunologic 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

174-177

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Davide Cossu (D)

Juntendo University, Department of Neurology, Tokyo, Japan; Juntendo University, Advanced Research Institute for Health Science, Tokyo, Japan.

Kazumasa Yokoyama (K)

Juntendo University, Department of Neurology, Tokyo, Japan; Juntendo University, Department of Treatment and Research in Multiple Sclerosis and Neuro-intractable disease, Tokyo, Japan. Electronic address: kazumasa@juntendo.ac.jp.

Tamami Sakanishi (T)

Juntendo University, Division of Cell Biology, Tokyo, Japan.

Eiichi Momotani (E)

Comparative Medical Research Institute, Laboratory of Immunopathology, Tsukuba, Japan.

Nobutaka Hattori (N)

Juntendo University, Department of Neurology, Tokyo, Japan; Juntendo University, Department of Treatment and Research in Multiple Sclerosis and Neuro-intractable disease, Tokyo, Japan.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Adjuvants immunologiques › Adjuvant and antigenic properties of...
questionsmedicales.fr › Eucaryotes › Animaux › Adjuvant and antigenic properties of...
questionsmedicales.fr › Techniques d'investigation › Modèles animaux › Maladie neurologique auto-immune expérimentale › Encéphalomyélite auto-immune expérimentale › Adjuvant and antigenic properties of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Adjuvant and antigenic properties of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Adjuvant and antigenic properties of...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Mycobacterium › Mycobacterium avium › Mycobacterium avium ssp. paratuberculosis › Adjuvant and antigenic properties of...