Hypercapnic BOLD MRI compared to H


Journal

NeuroImage. Clinical
ISSN: 2213-1582
Titre abrégé: Neuroimage Clin
Pays: Netherlands
ID NLM: 101597070

Informations de publication

Date de publication:
2019
Historique:
received: 18 11 2018
revised: 14 01 2019
accepted: 03 02 2019
pubmed: 12 2 2019
medline: 21 12 2019
entrez: 12 2 2019
Statut: ppublish

Résumé

Patients with Moyamoya Disease (MMD) need hemodynamic evaluation of vascular territories at risk of stroke. Today's investigative standards include H CO 20 consecutive patients fulfilled the inclusion criteria, a total of 160 vascular territories were analyzed retrospectively. Visual analysis (4-step visual rating system) of standardized, color-coded cerebrovascular reserve/reactivity maps showed a very strong correlation (Spearman's rho = 0.9, P < 0.001) between both modalities. Likewise, comparison of approximated regional perfusion changes across vascular territories (normalized to cerebellar change) reveal a highly significant correlation between both methods (Pearson's r = 0.71, P < 0.001). The present analysis indicates that CO

Sections du résumé

BACKGROUND AND PURPOSE
Patients with Moyamoya Disease (MMD) need hemodynamic evaluation of vascular territories at risk of stroke. Today's investigative standards include H
METHODS
CO
RESULTS
20 consecutive patients fulfilled the inclusion criteria, a total of 160 vascular territories were analyzed retrospectively. Visual analysis (4-step visual rating system) of standardized, color-coded cerebrovascular reserve/reactivity maps showed a very strong correlation (Spearman's rho = 0.9, P < 0.001) between both modalities. Likewise, comparison of approximated regional perfusion changes across vascular territories (normalized to cerebellar change) reveal a highly significant correlation between both methods (Pearson's r = 0.71, P < 0.001).
CONCLUSIONS
The present analysis indicates that CO

Identifiants

pubmed: 30743136
pii: S2213-1582(19)30063-4
doi: 10.1016/j.nicl.2019.101713
pmc: PMC6370561
pii:
doi:

Substances chimiques

Oxygen Radioisotopes 0
Radiopharmaceuticals 0

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

101713

Informations de copyright

Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.

Références

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Auteurs

Till-Karsten Hauser (TK)

Department of Neuroradiology, Eberhard Karls University Tübingen, Germany.

Achim Seeger (A)

Department of Neuroradiology, Eberhard Karls University Tübingen, Germany.

Benjamin Bender (B)

Department of Neuroradiology, Eberhard Karls University Tübingen, Germany.

Uwe Klose (U)

Department of Neuroradiology, Eberhard Karls University Tübingen, Germany.

Johannes Thurow (J)

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Ulrike Ernemann (U)

Department of Neuroradiology, Eberhard Karls University Tübingen, Germany.

Marcos Tatagiba (M)

Department of Neurosurgery, Eberhard Karls University Tübingen, Germany.

Philipp T Meyer (PT)

Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Nadia Khan (N)

Department of Neurosurgery, Eberhard Karls University Tübingen, Germany; Moyamoya Center, Division of Pediatric Neurosurgery, University Children's Hospital Zürich, Switzerland. Electronic address: moyamoya@neurochirurgie-tuebingen.de.

Constantin Roder (C)

Department of Neurosurgery, Eberhard Karls University Tübingen, Germany.

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